BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/12/2026 11:20:21 AM | Browse: 1 | Download: 1
 |
Received |
|
2025-09-01 07:15 |
|
Peer-Review Started |
|
2025-09-01 07:15 |
|
First Decision by Editorial Office Director |
|
2025-10-10 08:59 |
|
Return for Revision |
|
2025-10-10 08:59 |
|
Revised |
|
2025-10-22 11:40 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-12-24 02:37 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-12-24 07:24 |
|
Articles in Press |
|
2025-12-24 07:24 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-01-26 10:33 |
|
Publish the Manuscript Online |
|
2026-02-12 11:20 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Adipokine profiles reflect metabolic dysfunction but not fibrosis in patients with primary biliary cholangitis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Tomas Koky, Sylvia Drazilova, Slavomira Komarova, Marian Macej, Dominika Toporcerova, Martin Janicko, Ivana Spakova, Miroslava Rabajdova, Maria Marekova and Peter Jarcuska |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Sylvia Drazilova, Associate Professor, MD, PhD, Faculty of Medicine, PJ Safarik University, Trieda SNP 1, Kosice 04011, Slovakia. drazilovasylvia@gmail.com |
| Key Words |
Primary biliary cholangitis; Adipokines; Liver fibrosis; Metabolic dysfunction-associated steatotic liver disease; Metabolic syndrome |
| Core Tip |
Our results show that primary biliary cholangitis (PBC) patients with metabolic dysfunction-associated steatotic liver disease or metabolic syndrome as comorbidities exhibit significantly lower adiponectin levels, higher leptin levels, and an elevated leptin-to-adiponectin ratio within the limited sample size of this study. Thus, adipokines may serve as potential biomarkers for identifying metabolic conditions in PBC. By contrast, no significant associations were observed between adipokine levels and fibrosis severity or biochemical response. Our findings indicate that adipokines, particularly leptin-to-adiponectin ratio may become a promising biomarker for identifying metabolic dysfunction-associated steatotic liver disease in PBC patients. |
| Publish Date |
2026-02-12 11:20 |
| Citation |
Koky T, Drazilova S, Komarova S, Macej M, Toporcerova D, Janicko M, Spakova I, Rabajdova M, Marekova M, Jarcuska P. Adipokine profiles reflect metabolic dysfunction but not fibrosis in patients with primary biliary cholangitis. World J Hepatol 2026; 18(2): 113685 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i2/113685.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i2.113685 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
