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1/28/2026 9:23:39 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 113693
Country United States
Received
2025-09-01 09:46
Peer-Review Started
2025-09-01 09:48
First Decision by Editorial Office Director
2025-10-18 02:31
Return for Revision
2025-10-18 02:31
Revised
2025-10-31 21:27
Publication Fee Transferred
Second Decision by Editor
2025-12-22 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-22 07:49
Articles in Press
2025-12-22 07:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-20 00:31
Publish the Manuscript Online
2026-01-28 09:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Meta-Analysis
Article Title Mac-2 binding protein glycosylation isomer as a novel serum biomarker for recurrence in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Kyle R Stephens, Megan Wilson, Manting Xu, Jeremy T Gaskins, Gina Genova and Robert C G Martin II
ORCID
Author(s) ORCID Number
Kyle R Stephens http://orcid.org/0009-0008-1479-0580
Funding Agency and Grant Number
Corresponding Author Robert C G Martin II, MD, PhD, Division of Surgical Oncology, Hiram C Polk Jr, MD, Department of Surgery, University of Louisville, 315 E Broadway, Louisville, KY 40202, United States. robert.martin@louisville.edu
Key Words Hepatocellular carcinoma; Biomarker; Serum; Recurrence; Mac-2 binding protein glycosylation isomer
Core Tip Predicting tumor recurrence following curative treatment for hepatocellular carcinoma (HCC) remains a challenging task. Numerous novel biomarkers have been investigated for their ability to predict disease prognosis, as there is a clear need for noninvasive serum assays that can reliably assess the risk for post-treatment recurrence. Mac-2 binding protein glycosylation isomer (M2BPGi) has emerged as a serum biomarker for liver fibrosis, an important component of HCC pathogenesis. Our meta-analysis demonstrates M2BPGi’s utility as a pre-operative predictor of HCC recurrence.
Publish Date 2026-01-28 09:23
Citation

Stephens KR, Wilson M, Xu M, Gaskins JT, Genova G, Martin II RCG. Mac-2 binding protein glycosylation isomer as a novel serum biomarker for recurrence in hepatocellular carcinoma. World J Gastroenterol 2026; 32(5): 113693

URL https://www.wjgnet.com/1007-9327/full/v32/i5/113693.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i5.113693
Full Article (PDF) WJG-32-113693-with-cover.pdf
PRISMA 2009 Checklist 113693-PRISMA-2009-Checklist.pdf
Manuscript File 113693_Auto_Edited_112218.docx
Answering Reviewers 113693-answering-reviewers.pdf
Audio Core Tip 113693-audio.mp3
Biostatistics Review Certificate 113693-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113693-conflict-of-interest-statement.pdf
Copyright License Agreement 113693-copyright-assignment.pdf
Supplementary Material 113693-supplementary-material.pdf
Peer-review Report 113693-peer-reviews.pdf
Scientific Misconduct Check 113693-scientific-misconduct-check.png
Scientific Editor Work List 113693-scientific-editor-work-list.pdf
CrossCheck Report 113693-crosscheck-report.pdf