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2/4/2026 7:43:03 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 113699
Country Pakistan
Received
2025-09-02 05:49
Peer-Review Started
2025-09-02 05:49
First Decision by Editorial Office Director
2025-09-18 09:32
Return for Revision
2025-09-18 09:32
Revised
2025-10-02 08:13
Publication Fee Transferred
Second Decision by Editor
2025-12-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-17 07:06
Articles in Press
2025-12-17 07:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-29 07:25
Publish the Manuscript Online
2026-02-04 07:43
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Diagnostic accuracy and safety of endoscopic ultrasound-guided fine needle biopsy for evaluating mediastinal pathologies
Manuscript Source Invited Manuscript
All Author List Masood Muhammad Karim, Syedda Ayesha, Abdul Hadi Shahid, Muhammad Salman, Danaish Kumar, Zeeshan Uddin and Adeel Ur Rehman
ORCID
Author(s) ORCID Number
Masood Muhammad Karim http://orcid.org/0000-0002-2513-7842
Syedda Ayesha http://orcid.org/0009-0007-4893-3335
Abdul Hadi Shahid http://orcid.org/0009-0007-2392-3376
Muhammad Salman http://orcid.org/0009-0001-5556-0545
Adeel Ur Rehman http://orcid.org/0000-0001-8676-6119
Funding Agency and Grant Number
Corresponding Author Adeel Ur Rehman, Assistant Professor, Section of Gastroenterology, Department of Medicine, Aga Khan University, Karachi 74800, Sindh, Pakistan. rehman.adeel@aku.edu
Key Words Mediastinal mass; Mediastinal lymphadenopathy; Mediastinal lesion; Endoscopic ultrasound-guided fine needle biopsy; Malignancy; Diagnostic yield; Minimally invasive diagnosis and low- and middle-income countries
Core Tip Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is a minimally invasive technique that enables accurate tissue sampling of mediastinal lesions. In this single-centre study from Pakistan, EUS-FNB demonstrated excellent diagnostic performance, with 94.8% diagnostic yield, 88.9% sensitivity, and 100% specificity, while maintaining a strong safety profile without procedure-related complications. The study highlights the value of EUS-FNB in guiding management of both benign and malignant mediastinal pathologies and addressing a critical evidence gap in low- and middle-income country settings, where data remain limited.
Publish Date 2026-02-04 07:43
Citation

Karim MM, Ayesha S, Shahid AH, Salman M, Kumar D, Uddin Z, Rehman AU. Diagnostic accuracy and safety of endoscopic ultrasound-guided fine needle biopsy for evaluating mediastinal pathologies. World J Gastrointest Endosc 2026; 18(2): 113699

URL https://www.wjgnet.com/1948-5190/full/v18/i2/113699.htm
DOI https://dx.doi.org/10.4253/wjge.v18.i2.113699
Full Article (PDF) WJGE-18-113699-with-cover.pdf
STROBE Statement 113699-STROBE-statement.pdf
Manuscript File 113699_Auto_Edited_105617.docx
Answering Reviewers 113699-answering-reviewers.pdf
Audio Core Tip 113699-audio.mp3
Biostatistics Review Certificate 113699-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113699-conflict-of-interest-statement.pdf
Copyright License Agreement 113699-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113699-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113699-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113699-non-native-speakers.pdf
Peer-review Report 113699-peer-reviews.pdf
Scientific Misconduct Check 113699-scientific-misconduct-check.png
Scientific Editor Work List 113699-scientific-editor-work-list.pdf
CrossCheck Report 113699-crosscheck-report.pdf