BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/12/2026 12:25:38 PM | Browse: 110 | Download: 449
 |
Received |
|
2025-09-03 09:07 |
|
Peer-Review Started |
|
2025-09-03 09:07 |
|
First Decision by Editorial Office Director |
|
2025-10-11 06:57 |
|
Return for Revision |
|
2025-10-12 06:13 |
|
Revised |
|
2025-11-01 15:39 |
|
Publication Fee Transferred |
|
2025-11-05 14:03 |
|
Second Decision by Editor |
|
2025-12-23 02:37 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-12-23 09:19 |
|
Articles in Press |
|
2025-12-23 09:19 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-02-24 09:30 |
|
Publish the Manuscript Online |
|
2026-03-12 12:25 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fu-Chao Ma, Guan-Lan Zhang, Guo-Qiang Chen, Jing-Wen Ling, Yu-Feng Li, Bang-Teng Chi, Yu-Lu Tang, Wei Peng, Gang Chen, Dan-Ming Wei, Min-Hua Rong and Lian-Ying Ge |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangxi Zhuang Autonomous Region Health Commission Scientific Research Project |
Z-A20220465 |
| Guangxi Key Research and Development Plan |
AB20297021 |
| Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project |
S2022107 |
| China Undergraduate Innovation and Entrepreneurship Training Program |
S202310598074 |
| Future Academic Star of Guangxi Medical University |
WLXSZX23109 |
|
| Corresponding Author |
Lian-Ying Ge, Department of Endoscopy, Guangxi Medical University Cancer Hospital, No. 71 Hedi Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. gxgly@hotmail.com |
| Key Words |
Gastric cancer; MiR-27b-5p; cAMP response element-binding protein zinc finger; Signal transducer and activator of transcription 3 pathway; MicroRNAs |
| Core Tip |
Our findings provide preliminary evidence that reduction of miR-27b-5p restrains proliferation and migration of gastric cancer cells. Our investigation also indicates that elevated expression level of miR-27b-5p suppresses gene expression related to the signal transducer and activator of transcription 3 signaling pathway, mainly targeting cAMP response element-binding protein zinc finger. Specifically, this regulatory process includes upregulation of signal transducer and activator of transcription 3, cellular myelocytomatosis oncogene, cyclin D1, B-cell lymphoma 2, and survivin, as well as the downregulation of Bcl-2-associated X protein, Bcl-2-associated X protein/B-cell lymphoma 2 ratio, and cAMP response element-binding protein zinc finger. These molecular mechanisms enhance the proliferation of gastric cancer cells. |
| Publish Date |
2026-03-12 12:25 |
| Citation |
Ma FC, Zhang GL, Chen GQ, Ling JW, Li YF, Chi BT, Tang YL, Peng W, Chen G, Wei DM, Rong MH, Ge LY. MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway. World J Gastrointest Oncol 2026; 18(3): 113781
|
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i3/113781.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i3.113781 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
