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Publication Name World Journal of Gastroenterology
Manuscript ID 113810
Country France
Received
2025-09-04 06:26
Peer-Review Started
2025-09-04 06:26
First Decision by Editorial Office Director
2025-09-17 09:29
Return for Revision
2025-09-17 09:29
Revised
2025-10-01 07:00
Publication Fee Transferred
Second Decision by Editor
2025-11-24 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-24 09:11
Articles in Press
2025-11-24 09:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 01:50
Publish the Manuscript Online
2026-01-12 09:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Multibipolar radiofrequency vs single needle microwave ablation for the treatment of newly diagnosed hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Cécilia Bahloul, Agnès Rode, Pierre Pradat, Laurent Milot, Jérôme Dumortier, Philippe Merle, Jean-Yves Mabrut, Loïc Boussel and Angelo Della Corte
ORCID
Author(s) ORCID Number
Angelo Della Corte http://orcid.org/0000-0001-6773-877X
Funding Agency and Grant Number
Corresponding Author Angelo Della Corte, Department of Radiology, Hospices Civils de Lyon, 103 Gd Rue de la Croix-Rousse, Lyon 69002, Auvergne-Rhône-Alpes, France. a.dellacortetartaglione@gmail.com
Key Words Local tumor progression; Ablation; Microwave; Radiofrequency; Hepatocellular carcinoma
Core Tip There is limited data comparing multibipolar radiofrequency ablation (mbp-RFA) and microwave ablation (MWA) for treating hepatocellular carcinoma (HCC). This study analyzed 362 patients with newly diagnosed HCC who underwent either mbp-RFA (242 patients, 323 tumors) or MWA (120 patients, 168 tumors). Results showed that mbp-RFA provided better local tumor control, with a lower local tumor progression rate (11.4% vs 25.2%) and a higher complete ablation rate (94.1% vs 87.5%) compared to MWA. The advantage of mbp-RFA was particularly significant for tumors larger than 3 cm, where MWA had a local tumor progression rate of 60.9% vs 21.6% with mbp-RFA. Despite these differences in efficacy, both techniques had similar major complication rates (9.5% vs 7.5%). These findings suggest that mbp-RFA is a more effective option for larger, treatment-naïve HCC tumors while maintaining a comparable safety profile.
Publish Date 2026-01-12 09:50
Citation

Bahloul C, Rode A, Pradat P, Milot L, Dumortier J, Merle P, Mabrut JY, Boussel L, Della Corte A. Multibipolar radiofrequency vs single needle microwave ablation for the treatment of newly diagnosed hepatocellular carcinoma. World J Gastroenterol 2026; 32(2): 113810

URL https://www.wjgnet.com/1007-9327/full/v32/i2/113810.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i2.113810
Full Article (PDF) WJG-32-113810-with-cover.pdf
Manuscript File 113810_Auto_Edited_063734.docx
Answering Reviewers 113810-answering-reviewers.pdf
Audio Core Tip 113810-audio.mp3
Biostatistics Review Certificate 113810-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113810-conflict-of-interest-statement.pdf
Copyright License Agreement 113810-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113810-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113810-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113810-non-native-speakers.pdf
Supplementary Material 113810-supplementary-material.pdf
Peer-review Report 113810-peer-reviews.pdf
Scientific Misconduct Check 113810-scientific-misconduct-check.png
Scientific Editor Work List 113810-scientific-editor-work-list.pdf
CrossCheck Report 113810-crosscheck-report.pdf