12/24/2025 9:56:51 AM | Browse: 13 | Download: 51
| Publication Name | World Journal of Cardiology |
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| Manuscript ID | 113820 |
| Country | Pakistan |
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| ISSN | 1949-8462 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Transplantation | ||||||||
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| Manuscript Type | Systematic Reviews | ||||||||
| Article Title | Efficacy of ivabradine in heart rate reduction after cardiac transplantation: Systematic review and meta-analysis | ||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||
| All Author List | Faizan Ahmed, Ramsha Ali, Faseeh Haider, Haider Hussain Shah, Kanza Farhan, Kainat Jahangir, Madiha Kiyani, Muhammad Saad Khan, Zaima Afzaal, Shayan Iqbal Khan, Muhammad Abdullah Nizam, Muhammad Usman, Najam Gohar, Mushood Ahmed, Tehmasp Rehman Mirza, Yasar Sattar, Amro Taha, Jesus Almendral and Fawaz Alenezi | ||||||||
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| Corresponding Author | Muhammad Usman, Researcher, Department of Medicine, Ameer-Ud-Din Medical College, 6 Birdwood Road, Jinnah Town, Lahore 54000, Punjab, Pakistan. deustchusman23@gmail.com | ||||||||
| Key Words | Ivabradine; Heart transplant; Heart rate; Meta-analysis; Tachycardia; Decision making | ||||||||
| Core Tip | Persistent sinus tachycardia after heart transplantation is linked to graft dysfunction and poor outcomes, yet beta-blockers are often limited by hypotension or bradyarrhythmia. Ivabradine, a selective inhibitor of funny current, lowers heart rate (HR) without negative inotropic or hypotensive effects. Our systematic review and meta-analysis of four studies (264 patients) found ivabradine significantly reduced resting HR and was well tolerated in transplant patients, underscoring its role as a promising therapeutic option for rate control when conventional treatments are unsuitable. | ||||||||
| Publish Date | 2025-12-24 09:56 | ||||||||
| Citation | Ahmed F, Ali R, Haider F, Shah HH, Farhan K, Jahangir K, Kiyani M, Khan MS, Afzaal Z, Khan SI, Nizam MA, Usman M, Gohar N, Ahmed M, Mirza TR, Sattar Y, Taha A, Almendral J, Alenezi F. Efficacy of ivabradine in heart rate reduction after cardiac transplantation: Systematic review and meta-analysis. World J Cardiol 2025; 17(12): 113820 |
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| URL | https://www.wjgnet.com/1949-8462/full/v17/i12/113820.htm | ||||||||
| DOI | https://dx.doi.org/10.4330/wjc.v17.i12.113820 |
| Full Article (PDF) | WJC-17-113820-with-cover.pdf |
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| PRISMA 2009 Checklist | 113820-PRISMA-2009-Checklist.pdf |
| Manuscript File | 113820_Auto_Edited_020828.docx |
| Answering Reviewers | 113820-answering-reviewers.pdf |
| Audio Core Tip | 113820-audio.mp3 |
| Biostatistics Review Certificate | 113820-biostatistics-statement.pdf |
| Conflict-of-Interest Disclosure Form | 113820-conflict-of-interest-statement.pdf |
| Copyright License Agreement | 113820-copyright-assignment.pdf |
| Non-Native Speakers of English Editing Certificate | 113820-non-native-speakers.pdf |
| Peer-review Report | 113820-peer-reviews.pdf |
| Scientific Misconduct Check | 113820-scientific-misconduct-check.png |
| Scientific Editor Work List | 113820-scientific-editor-work-list.pdf |
| CrossCheck Report | 113820-crosscheck-report.pdf |