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5/18/2026 10:29:13 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 113841
Country Italy
Received
2025-09-08 14:02
Peer-Review Started
2025-09-08 14:05
First Decision by Editorial Office Director
2025-09-17 09:31
Return for Revision
2025-09-17 09:31
Revised
2026-01-08 17:51
Publication Fee Transferred
Second Decision by Editor
2026-03-05 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 09:30
Articles in Press
2026-03-05 09:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-29 01:35
Publish the Manuscript Online
2026-05-18 10:29
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Minireviews
Article Title Functional disorders in patients with chronic constipation: Review of the literature and personal experience
Manuscript Source Invited Manuscript
All Author List Mario Pescatori, Gerardo Perrotta and Paola De Nardi
ORCID
Author(s) ORCID Number
Mario Pescatori http://orcid.org/0000-0001-7571-5009
Paola De Nardi http://orcid.org/0000-0002-9337-6765
Funding Agency and Grant Number
Corresponding Author Mario Pescatori, FRCS, FRCS (Gen Surg), MD, Professor, Department of Coloproctology, Parioli Clinic, Via Courmayeur, 24, Rome 00100, Italy. ucpclub@virgilio.it
Key Words Constipation; Obstructed defecation; Anismus; Slow-transit; Rectal hyposensation
Core Tip Obstructed defecation is frequently driven by functional disorders that are often overlooked, leading to inappropriate surgical treatment and poor outcomes. Using the iceberg model, this editorial emphasizes that anxiety depression, anismus, rectal hyposensitivity, slow transit constipation, and pudendal neuropathy account for most hidden causes of obstructed defecation. Careful functional evaluation and multidisciplinary management allow surgery to be avoided in the majority of patients and significantly reduce treatment failure and complications. Surgery should be reserved for selected organic conditions, while functional disorders require targeted, non-surgical therapies to achieve durable symptom improvement.
Publish Date 2026-05-18 10:29
Citation

Pescatori M, Perrotta G, De Nardi P. Functional disorders in patients with chronic constipation: Review of the literature and personal experience. World J Gastroenterol 2026; 32(19): 113841

URL https://www.wjgnet.com/1007-9327/full/v32/i19/113841.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i19.113841
Full Article (PDF) WJG-32-113841-with-cover.pdf
Manuscript File 113841_Auto_Edited_012734.docx
Answering Reviewers 113841-answering-reviewers.pdf
Audio Core Tip 113841-audio.m4a
Conflict-of-Interest Disclosure Form 113841-conflict-of-interest-statement.pdf
Copyright License Agreement 113841-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113841-non-native-speakers.pdf
Peer-review Report 113841-peer-reviews.pdf
Scientific Misconduct Check 113841-scientific-misconduct-check.png
Scientific Editor Work List 113841-scientific-editor-work-list.pdf
CrossCheck Report 113841-crosscheck-report.pdf