BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/12/2026 9:18:16 AM | Browse: 4 | Download: 11
 |
Received |
|
2025-09-05 01:40 |
|
Peer-Review Started |
|
2025-09-05 07:32 |
|
First Decision by Editorial Office Director |
|
2025-10-17 07:20 |
|
Return for Revision |
|
2025-10-17 07:20 |
|
Revised |
|
2025-12-02 15:29 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-01-14 02:46 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-01-14 08:56 |
|
Articles in Press |
|
2026-01-14 08:56 |
|
Edit the Manuscript by Language Editor |
|
2026-01-19 17:27 |
|
Typeset the Manuscript |
|
2026-02-27 09:59 |
|
Publish the Manuscript Online |
|
2026-03-12 09:18 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Circulating microbiome and its clinical implications in diabetes mellitus: Mechanistic insights and therapeutic perspectives
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Dinakaran Vasudevan |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Dinakaran Vasudevan, PhD, Senior Scientist, Gut Microbiome Division, Scientific Knowledge on Aging and Neurological Ailments (SKAN) Research Trust, Happiest Health Office, No.141/2, Gate 4, St. John’s Research Institute, 100 Feet Road, KHB Block, John Nagar, Koramangala, Bangalore 560034, Karnataka, India. dinakaran.svgev@gmail.com |
| Key Words |
Circulating microbiome; Blood microbiome; Microbial components; Toll-like receptors; Trimethylamine N-oxide; Short chain fatty acids |
| Core Tip |
The circulating microbiome encompassing microbial DNA, products, and viable microbes detected in blood, links gut barrier dysfunction to chronic, low-grade inflammation in diabetes. Quantifying blood microbial signatures (16S rDNA/cell free DNA, endotoxin activity, metabolites) may enable early risk stratification for insulin resistance and prediction of micro- and macrovascular complications. Integrating longitudinal cell free microbiome profiling with glycaemic and inflammatory indices could refine diagnosis, personalize therapy, and monitor responses to interventions (dietary fiber, pre/probiotics, postbiotics, barrier-restoring strategies, and microbiome-informed pharmacotherapy such as metformin). Standardized sampling, contamination control, and causal studies are critical to translate these insights into routine diabetes care. |
| Publish Date |
2026-03-12 09:18 |
| Citation |
Vasudevan D. Circulating microbiome and its clinical implications in diabetes mellitus: Mechanistic insights and therapeutic perspectives. World J Diabetes 2026; 17(3): 113843 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i3/113843.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i3.113843 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
