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2/11/2026 7:19:24 AM | Browse: 4 | Download: 30
Publication Name World Journal of Gastroenterology
Manuscript ID 113861
Country United States
Received
2025-09-08 05:21
Peer-Review Started
2025-09-08 05:21
First Decision by Editorial Office Director
2025-10-11 07:03
Return for Revision
2025-10-11 07:03
Revised
2025-11-10 18:16
Publication Fee Transferred
Second Decision by Editor
2026-01-06 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-06 04:35
Articles in Press
2026-01-06 04:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-04 00:32
Publish the Manuscript Online
2026-02-11 07:19
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Use of Y-90 radioembolization to control liver metastases in pancreatic acinar cell carcinoma and pancreatoblastoma: Two case reports
Manuscript Source Unsolicited Manuscript
All Author List Nebojsa Skorupan, David Sperling, Charles Nutting, Markku Miettinen, Allen Cohn and Christine Alewine
ORCID
Author(s) ORCID Number
Christine Alewine http://orcid.org/0000-0003-1661-0957
Funding Agency and Grant Number
Funding Agency Grant Number
Intramural Research Program of the Center for Cancer Research, National Cancer Institute, National Institutes of Health ZIA BC 012041
Corresponding Author Christine Alewine, Associate Professor, Department of Medicine, Dartmouth Cancer Center, One Medical Center Drive, Williamson 571, Lebanon, NH 03756, United States. christine.alewine@dartmouth.edu
Key Words Acinar cell carcinoma of the pancreas; Pancreatoblastoma; Yttrium-90 radioembolization; Rare pancreatic tumors; Transarterial radioembolization; Case report
Core Tip We report the use of Yttrium-90 (Y-90) radioembolization in pancreatic acinar cell carcinoma and adult pancreatoblastoma hepatic metastases. Both patients achieved durable partial responses with multiple Y-90 treatments over extended periods, and tolerated the therapy well. These rare exocrine pancreatic malignancies exhibited marked radiosensitivity, supporting early consideration of Y-90 radioembolization in liver-dominant disease. The successful integration with systemic therapies and ability to repeat treatments safely over multi-year intervals highlights Y-90’s potential as a cornerstone locoregional therapy for these challenging cancers.
Publish Date 2026-02-11 07:19
Citation

Skorupan N, Sperling D, Nutting C, Miettinen M, Cohn A, Alewine C. Use of Y-90 radioembolization to control liver metastases in pancreatic acinar cell carcinoma and pancreatoblastoma: Two case reports. World J Gastroenterol 2026; 32(8): 113861

URL https://www.wjgnet.com/1007-9327/full/v32/i8/113861.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i8.113861
Full Article (PDF) WJG-32-113861-with-cover.pdf
CARE Checklist–2016 113861-CARE-Checklist-2016.pdf
Manuscript File 113861_Auto_Edited_072526-v2.docx
Answering Reviewers 113861-answering-reviewers.pdf
Audio Core Tip 113861-audio.mp3
Conflict-of-Interest Disclosure Form 113861-conflict-of-interest-statement.pdf
Copyright License Agreement 113861-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 113861-informed-consent-statement.pdf
Peer-review Report 113861-peer-reviews.pdf
Scientific Misconduct Check 113861-scientific-misconduct-check.png
Scientific Editor Work List 113861-scientific-editor-work-list.pdf
CrossCheck Report 113861-crosscheck-report.pdf