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7/24/2026 10:16:23 AM | Browse: 1 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 113871
Country Saudi Arabia
Received
2025-09-05 03:19
Peer-Review Started
2025-09-05 03:36
First Decision by Editorial Office Director
2025-10-21 06:44
Return for Revision
2025-10-21 06:44
Revised
2025-11-17 05:59
Publication Fee Transferred
Second Decision by Editor
2026-01-27 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-27 08:46
Articles in Press
2026-01-27 08:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-21 01:06
Publish the Manuscript Online
2026-07-24 10:16
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell & Tissue Engineering
Manuscript Type Editorial
Article Title Mesenchymal stem cell secretome and exosomes as potential advanced therapy medicinal products for treating a failing heart
Manuscript Source Invited Manuscript
All Author List Syed Mohammad Habib, Mohammad Fateh Martini, Yacoub Nail Hamdan Abu-Hamdan, Omran Mohammed Marwan Shrebaty and Khawaja Husnain Haider
ORCID
Author(s) ORCID Number
Khawaja Husnain Haider http://orcid.org/0000-0002-7907-4808
Funding Agency and Grant Number
Corresponding Author Khawaja Husnain Haider, PhD, Professor, Department of Basic Sciences, Sulaiman Alrajhi Medical School, PO Box 777, Al Bukairiyah 51941, Saudi Arabia. khhaider@gmail.com
Key Words Cell-free therapy; Conditioned medium; Exosomes; Heart failure; Mesenchymal stem cells; Myocardial infarction; Secretome
Core Tip This paper reviews advancements in the treatment and management of heart failure through cell-free therapies, including mesenchymal stem cell-derived secretomes and exosomes that deliver an array of bioactive molecules and participate in the repair process. The seven primary modules, which explain the reparative and regenerative potential of secretome and exosomes, have been discussed in the context of mechanistic understanding, drawing on published data from experimental and clinical settings that act on the myocardium to achieve the therapeutic benefits of the treatment.
Publish Date 2026-07-24 10:16
Citation

Habib SM, Martini MF, Abu-Hamdan YNH, Shrebaty OMM, Haider KH. Mesenchymal stem cell secretome and exosomes as potential advanced therapy medicinal products for treating a failing heart. World J Stem Cells 2026; 18(7): 113871

URL https://www.wjgnet.com/1948-0210/full/v18/i7/113871.htm
DOI https://doi.org/10.4252/wjsc.113871
Full Article (PDF) WJSC-18-113871-with-cover.pdf
Manuscript File 113871_Auto_Edited_011203.docx
Answering Reviewers 113871-answering-reviewers.pdf
Audio Core Tip 113871-audio.mp3
Conflict-of-Interest Disclosure Form 113871-conflict-of-interest-statement.pdf
Copyright License Agreement 113871-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113871-non-native-speakers.pdf
Supplementary Material 113871-supplementary-material.pdf
Peer-review Report 113871-peer-reviews.pdf
Scientific Misconduct Check 113871-scientific-misconduct-check.png
Scientific Editor Work List 113871-scientific-editor-work-list.pdf
CrossCheck Report 113871-crosscheck-report.pdf