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3/19/2026 7:07:30 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 113939
Country China
Received
2025-09-08 10:35
Peer-Review Started
2025-09-08 10:36
First Decision by Editorial Office Director
2025-10-11 07:20
Return for Revision
2025-10-11 07:20
Revised
2025-10-24 17:33
Publication Fee Transferred
2025-10-28 14:23
Second Decision by Editor
2026-01-28 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-28 09:21
Articles in Press
2026-01-28 09:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-06 00:10
Publish the Manuscript Online
2026-03-19 07:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis
Manuscript Source Unsolicited Manuscript
All Author List Xu Han, Miao-Yang Chen, Qing-Fang Xiong, Yan-Dan Zhong, Du-Xian Liu, Jia Li and Yong-Feng Yang
ORCID
Author(s) ORCID Number
Xu Han http://orcid.org/0000-0003-3562-2822
Miao-Yang Chen http://orcid.org/0000-0002-6597-6261
Qing-Fang Xiong http://orcid.org/0000-0001-6746-9389
Yan-Dan Zhong http://orcid.org/0000-0003-4580-9375
Du-Xian Liu http://orcid.org/0000-0003-1210-7596
Jia Li http://orcid.org/0000-0003-0100-417X
Yong-Feng Yang http://orcid.org/0000-0002-3214-0038
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81970454
Key Projects of Jiangsu Provincial Health Commission ZD2021061
Corresponding Author Yong-Feng Yang, Chief Physician, PhD, Professor, Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, No. 1 Zhongfu Road, Gulou District, Nanjing 210003, Jiangsu Province, China. yangyongfeng@njucm.edu.cn
Key Words Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis; Ballooned hepatocytes; Cytokeratin 8/18; Sonic hedgehog
Core Tip This is a retrospective cohort study of the characteristics of metabolic dysfunction-associated steatohepatitis, in which we found the suggestive role of sonic hedgehog immunostaining in the diagnosis of metabolic dysfunction-associated steatohepatitis. We also found that histological ballooning hepatocytes and circulating M30 as independent predictors of advanced fibrosis.
Publish Date 2026-03-19 07:07
Citation

Han X, Chen MY, Xiong QF, Zhong YD, Liu DX, Li J, Yang YF. Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(12): 113939

URL https://www.wjgnet.com/1007-9327/full/v32/i12/113939.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i12.113939
Full Article (PDF) WJG-32-113939-with-cover.pdf
STROBE Statement 113939-STROBE-statement.pdf
Manuscript File 113939_Auto_Edited_070239.docx
Answering Reviewers 113939-answering-reviewers.pdf
Audio Core Tip 113939-audio.m4a
Biostatistics Review Certificate 113939-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113939-conflict-of-interest-statement.pdf
Copyright License Agreement 113939-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113939-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113939-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113939-non-native-speakers.pdf
Peer-review Report 113939-peer-reviews.pdf
Scientific Misconduct Check 113939-scientific-misconduct-check.png
Scientific Editor Work List 113939-scientific-editor-work-list.pdf
CrossCheck Report 113939-crosscheck-report.pdf