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3/12/2026 9:18:16 AM | Browse: 5 | Download: 36
Publication Name World Journal of Diabetes
Manuscript ID 113947
Country China
Received
2025-09-08 06:24
Peer-Review Started
2025-09-12 00:15
First Decision by Editorial Office Director
2025-10-23 08:13
Return for Revision
2025-10-23 08:13
Revised
2025-10-25 10:36
Publication Fee Transferred
Second Decision by Editor
2025-12-18 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-25 07:59
Articles in Press
2025-12-25 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-26 09:03
Publish the Manuscript Online
2026-03-12 09:18
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population
Manuscript Source Unsolicited Manuscript
All Author List Nan Li, Yu-Peng Li, Qing Xu, Jian Xu, Yi-Hong Yu, Juan Su, Chong Shen, Jiang-Yi Yu and Harvest F Gu
ORCID
Author(s) ORCID Number
Nan Li http://orcid.org/0000-0002-3341-2373
Jiang-Yi Yu http://orcid.org/0000-0001-7159-5396
Harvest F Gu http://orcid.org/0000-0003-4578-5449
Funding Agency and Grant Number
Funding Agency Grant Number
Excellent Doctor Program of Jiangsu Province Hospital of Chinese Medicine 20221222
Launch Grant of China Pharmaceutical University 20180815
Corresponding Author Harvest F Gu, Laboratory of Molecular Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, No. 24 Tongjia Alley, Gulou District, Nanjing 210009, Jiangsu Province, China. feng.gu@cpu.edu.cn
Key Words Diabetic kidney disease; DNA methylation; Solute carrier family 30 member 8; Type 2 diabetes; Hypermethylation
Core Tip Solute carrier family 30 member 8 (SLC30A8) is a β-cell specific Zn transporter in insulin secretory granules. DNA in the SLC30A8 gene promoter region is hypermethylated. SLC30A8 promoter hypermethylation is associated with both type 2 diabetes and diabetic kidney disease. This study aims to evaluate whether DNA methylation changes in SLC30A8 is associated with type 2 diabetes and diabetic kidney disease.
Publish Date 2026-03-12 09:18
Citation

Li N, Li YP, Xu Q, Xu J, Yu YH, Su J, Shen C, Yu JY, Gu HF. SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population. World J Diabetes 2026; 17(3): 113947

URL https://www.wjgnet.com/1948-9358/full/v17/i3/113947.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i3.113947
Full Article (PDF) WJD-17-113947-with-cover.pdf
The ARRIVE Guidelines 113947-The-ARRIVE-Guidelines.pdf
Manuscript File 113947_Auto_Edited_025745.docx
Answering Reviewers 113947-answering-reviewers.pdf
Audio Core Tip 113947-audio.m4a
Biostatistics Review Certificate 113947-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113947-conflict-of-interest-statement.pdf
Copyright License Agreement 113947-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 113947-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 113947-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113947-non-native-speakers.pdf
Supplementary Material 113947-supplementary-material.pdf
Peer-review Report 113947-peer-reviews.pdf
Journal Editor-in-Chief Review Report 113947-journal-editor-in-chief.pdf
Scientific Misconduct Check 113947-scientific-misconduct-check.png
Scientific Editor Work List 113947-scientific-editor-work-list.pdf
CrossCheck Report 113947-crosscheck-report.pdf