BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/3/2026 6:28:04 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 113995
Country China
Received
2025-09-09 02:20
Peer-Review Started
2025-09-09 02:21
First Decision by Editorial Office Director
2025-10-11 07:31
Return for Revision
2025-10-11 10:26
Revised
2025-10-23 05:11
Publication Fee Transferred
2025-10-30 08:10
Second Decision by Editor
2025-12-09 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-10 06:17
Articles in Press
2025-12-10 06:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-26 15:43
Publish the Manuscript Online
2026-02-03 06:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Recent advances in spasmolytic polypeptide expressing metaplasia research
Manuscript Source Unsolicited Manuscript
All Author List Rui-Rui Yang, Ya-Ru Yan and Yu-Feng Li
ORCID
Author(s) ORCID Number
Yu-Feng Li http://orcid.org/0009-0005-3860-8411
Funding Agency and Grant Number
Funding Agency Grant Number
Liaoning Provincial Science and Technology Plan Joint Plan (Applied Basic Research Program) 2023JH2/101700226
Liaoning Provincial Traditional Chinese Medicine Interdisciplinary Innovation Team Project LNZYYCXTD-JCCX-002
Corresponding Author Yu-Feng Li, Chief Physician, Professor, Research Assistant Professor, Department of Gastroenterology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Huanggu District, Shenyang 110847, Liaoning Province, China. 3278086072@qq.com
Key Words Gastric adenocarcinoma; Spasmolytic polypeptide-expressing metaplasia; Signaling pathway; Research progress; Pathogenesis
Core Tip Gastric cancer is one of the most common cancers worldwide, with exceptionally high morbidity and fatality rates. A thorough investigation of the pathophysiology of spasmolytic polypeptide-expressing metaplasia (SPEM) is required. SPEM serves as a critical nexus between mucosal repair and gastric carcinogenesis and is a valuable target for early detection and intervention. To gain a deeper understanding of SPEM, this review summarizes its recent mechanistic roles in gastric mucosal diseases. By elucidating these mechanisms, this review aims to provide deeper insights into the research and prevention of SPEM-related diseases.
Publish Date 2026-02-03 06:28
Citation

Yang RR, Yan YR, Li YF. Recent advances in spasmolytic polypeptide expressing metaplasia research. World J Gastrointest Oncol 2026; 18(2): 113995

URL https://www.wjgnet.com/1948-5204/full/v18/i2/113995.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i2.113995
Full Article (PDF) WJGO-18-113995-with-cover.pdf
Manuscript File 113995_Auto_Edited_022151.docx
Answering Reviewers 113995-answering-reviewers.pdf
Audio Core Tip 113995-audio.m4a
Conflict-of-Interest Disclosure Form 113995-conflict-of-interest-statement.pdf
Copyright License Agreement 113995-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113995-non-native-speakers.pdf
Peer-review Report 113995-peer-reviews.pdf
Scientific Misconduct Check 113995-scientific-misconduct-check.png
Scientific Editor Work List 113995-scientific-editor-work-list.pdf
CrossCheck Report 113995-crosscheck-report.pdf