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Articles Published Processes
11/26/2025 3:57:04 AM | Browse: 92 | Download: 281
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Received |
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2025-09-10 06:32 |
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Peer-Review Started |
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2025-09-10 06:32 |
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First Decision by Editorial Office Director |
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2025-09-28 09:28 |
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Return for Revision |
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2025-09-28 09:28 |
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Revised |
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2025-10-09 05:10 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-28 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-28 09:40 |
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Articles in Press |
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2025-10-28 09:40 |
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Edit the Manuscript by Language Editor |
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2025-11-04 06:21 |
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Typeset the Manuscript |
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2025-11-19 01:21 |
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Publish the Manuscript Online |
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2025-11-26 03:57 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
CD146-positive mesenchymal stromal cells: A promising subtype for enhanced acute respiratory distress syndrome therapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bin Li, Rui-Xi Ming, Yu-Meng Liu and Tang-Jie Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Basic Research Program of Jiangsu Province (2024) |
BK20240907 |
| “Lv Yang Jin Feng” Outstanding Doctor of Yangzhou |
YZLYJFJH2023YXBS169 |
| Top-Level Talents Support Program of Yangzhou University |
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| Corresponding Author |
Bin Li, Assistant Professor, PhD, Professor, Institute of Comparative Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, No. 88 Daxue South Road, Yangzhou 225009, Jiangsu Province, China. 008480@yzu.edu.cn |
| Key Words |
CD146; Mesenchymal stromal cell; Acute respiratory distress syndrome; Nuclear factor kappa B; Cyclooxygenase-2; Prostaglandin E2 |
| Core Tip |
This article presents evidence that CD146+ mesenchymal stromal cells define a high-potency subpopulation for acute respiratory distress syndrome therapy by engaging a nuclear factor kappa B → cyclooxygenase-2 paracrine signaling program. Enriching or priming mesenchymal stromal cells for CD146 expression and nuclear factor kappa B/cyclooxygenase-2 activity may yield practical potency biomarkers and enable more consistent, mechanism-driven cell therapies that more effectively restore alveolar-capillary barrier integrity. |
| Publish Date |
2025-11-26 03:57 |
| Citation |
Li B, Ming RX, Liu YM, Zhang TJ. CD146-positive mesenchymal stromal cells: A promising subtype for enhanced acute respiratory distress syndrome therapy. World J Stem Cells 2025; 17(11): 114031 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i11/114031.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i11.114031 |
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