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11/26/2025 3:57:04 AM | Browse: 12 | Download: 23
Publication Name World Journal of Stem Cells
Manuscript ID 114031
Country China
Received
2025-09-10 06:32
Peer-Review Started
2025-09-10 06:32
First Decision by Editorial Office Director
2025-09-28 09:28
Return for Revision
2025-09-28 09:28
Revised
2025-10-09 05:10
Publication Fee Transferred
Second Decision by Editor
2025-10-28 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-28 09:40
Articles in Press
2025-10-28 09:40
Edit the Manuscript by Language Editor
2025-11-04 06:21
Typeset the Manuscript
2025-11-19 01:21
Publish the Manuscript Online
2025-11-26 03:57
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biology
Manuscript Type Letter to the Editor
Article Title CD146-positive mesenchymal stromal cells: A promising subtype for enhanced acute respiratory distress syndrome therapy
Manuscript Source Invited Manuscript
All Author List Bin Li, Rui-Xi Ming, Yu-Meng Liu and Tang-Jie Zhang
ORCID
Author(s) ORCID Number
Bin Li http://orcid.org/0000-0003-2882-7512
Funding Agency and Grant Number
Funding Agency Grant Number
Basic Research Program of Jiangsu Province (2024) BK20240907
“Lv Yang Jin Feng” Outstanding Doctor of Yangzhou YZLYJFJH2023YXBS169
Top-Level Talents Support Program of Yangzhou University
Corresponding Author Bin Li, Assistant Professor, PhD, Professor, Institute of Comparative Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, No. 88 Daxue South Road, Yangzhou 225009, Jiangsu Province, China. 008480@yzu.edu.cn
Key Words CD146; Mesenchymal stromal cell; Acute respiratory distress syndrome; Nuclear factor kappa B; Cyclooxygenase-2; Prostaglandin E2
Core Tip This article presents evidence that CD146+ mesenchymal stromal cells define a high-potency subpopulation for acute respiratory distress syndrome therapy by engaging a nuclear factor kappa B → cyclooxygenase-2 paracrine signaling program. Enriching or priming mesenchymal stromal cells for CD146 expression and nuclear factor kappa B/cyclooxygenase-2 activity may yield practical potency biomarkers and enable more consistent, mechanism-driven cell therapies that more effectively restore alveolar-capillary barrier integrity.
Publish Date 2025-11-26 03:57
Citation

Li B, Ming RX, Liu YM, Zhang TJ. CD146-positive mesenchymal stromal cells: A promising subtype for enhanced acute respiratory distress syndrome therapy. World J Stem Cells 2025; 17(11): 114031

URL https://www.wjgnet.com/1948-0210/full/v17/i11/114031.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i11.114031
Full Article (PDF) WJSC-17-114031-with-cover.pdf
Manuscript File 114031_Auto_Edited_012239.docx
Answering Reviewers 114031-answering-reviewers.pdf
Audio Core Tip 114031-audio.mp3
Conflict-of-Interest Disclosure Form 114031-conflict-of-interest-statement.pdf
Copyright License Agreement 114031-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114031-non-native-speakers.pdf
Peer-review Report 114031-peer-reviews.pdf
Scientific Misconduct Check 114031-scientific-misconduct-check.png
Scientific Editor Work List 114031-scientific-editor-work-list.pdf
CrossCheck Report 114031-crosscheck-report.pdf