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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 114066
Country China
Received
2025-09-28 08:50
Peer-Review Started
2025-09-28 08:50
First Decision by Editorial Office Director
2025-10-21 06:24
Return for Revision
2025-10-21 06:24
Revised
2025-11-04 05:03
Publication Fee Transferred
2025-11-12 10:27
Second Decision by Editor
2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 05:53
Articles in Press
2025-12-01 05:53
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-26 08:25
Publish the Manuscript Online
2026-02-03 06:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Imaging Science & Photographic Technology
Manuscript Type Retrospective Study
Article Title Computed tomography with carcinoembryonic antigen and carbohydrate antigen 19-9 in diagnosing lymph node metastasis of early gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Hong-Zhi Chen, Ping Zhang and Jun Ma
ORCID
Author(s) ORCID Number
Ping Zhang http://orcid.org/0009-0008-2019-3184
Funding Agency and Grant Number
Corresponding Author Ping Zhang, Deputy Director, Imaging department, Huai'an Clinical Medical College of Jiangsu University Huai'an Hospital of Huai'an City, Huaian Hospital of Huaian City , Department of Radiology, Huai’an 223200, Jiangsu Province, China. 3461905@163.com
Key Words Computed tomography; Carcinoembryonic antigen; Carbohydrate antigen 19-9; Gastric cancer; Lymph node metastasis
Core Tip This study identified that elevated computed tomography (CT) values and increased short-axis diameter of lymph nodes, along with raised serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels, are key indicators for lymph node metastasis in early gastric cancer. Combining anatomical imaging with tumor biomarker analysis improved diagnostic sensitivity and reduced the missed diagnosis rate by 6.67%-8.33% compared to using CT alone. These findings highlight the value of integrating morphological and biological data for more accurate metastasis detection, filling a gap in current diagnostic approaches and highlights the need for multimodal strategies in optimizing individualized treatment decisions.
Publish Date 2026-02-03 06:28
Citation

Chen HZ, Zhang P, Ma J. Computed tomography with carcinoembryonic antigen and carbohydrate antigen 19-9 in diagnosing lymph node metastasis of early gastric cancer. World J Gastrointest Oncol 2026; 18(2): 114066

URL https://www.wjgnet.com/1948-5204/full/v18/i2/114066.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i2.114066
Full Article (PDF) WJGO-18-114066-with-cover.pdf
Manuscript File 114066_Auto_Edited_035123.docx
Answering Reviewers 114066-answering-reviewers.pdf
Audio Core Tip 114066-audio.mp3
Biostatistics Review Certificate 114066-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114066-conflict-of-interest-statement.pdf
Copyright License Agreement 114066-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114066-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114066-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114066-non-native-speakers.pdf
Peer-review Report 114066-peer-reviews.pdf
Scientific Misconduct Check 114066-scientific-misconduct-check.png
Scientific Editor Work List 114066-scientific-editor-work-list.pdf
CrossCheck Report 114066-crosscheck-report.pdf