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Articles Published Processes
6/26/2026 9:50:23 AM | Browse: 0 | Download: 0
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Received |
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2025-09-15 02:42 |
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Peer-Review Started |
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2025-09-15 02:42 |
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First Decision by Editorial Office Director |
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2025-11-04 08:06 |
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Return for Revision |
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2025-11-04 08:06 |
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Revised |
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2025-11-12 00:24 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-08 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-08 10:00 |
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Articles in Press |
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2026-01-08 10:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-16 11:11 |
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Publish the Manuscript Online |
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2026-06-26 09:50 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Food Science & Technology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Advancing mechanistic and translational insights into ginger-extract-mediated protection against acrylamide-induced liver injury
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xu Cui, Zhi-Qiang Chen and Liu Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fujian Provincial Science and Technology Innovation Joint Fund Project |
No. 2024Y9555 |
| Youth Research Project of the Science and Technology Plan of Fujian Provincial Health Commission |
No. 2024QNB005 |
| Fujian Provincial Natural Science Foundation Project |
No. 2025J01226 |
| Fuian Provincial Medical Project for Creating Dual High-Quality Development (High Level and High Standard) |
No. ETK2025004 |
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| Corresponding Author |
Xu Cui, Department of Pediatric Surgery, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, No. 18 Daoshan Road, Fuzhou 350001, Fujian Province, China. 16802937@qq.com |
| Key Words |
Ginger extract; Acrylamide-induced liver injury; Metabolomics; Hepatoprotection; Therapeutic agents |
| Core Tip |
This article highlights critical gaps in current research on ginger extract's hepatoprotective effects against acrylamide-induced liver injury - namely, the undefined material basis of active components and superficial mechanistic insights. It proposes actionable solutions: Leveraging portal venous metabolomics, liver liquid chromatography-mass spectrometry profiling, and single-cell transcriptomics to map protective metabolites and molecular changes; validating mechanisms via primary hepatocyte assays (apoptosis, inflammation, oxidative stress); and applying high-throughput screening (genetic editing) to uncover target pathways. These directions are pivotal to transforming phenotypic observations into mechanistically robust, translatable insights for ginger-based liver protection. |
| Publish Date |
2026-06-26 09:50 |
| Citation |
Cui X, Chen ZQ, Chen L. Letter to the Editor: Advancing mechanistic and translational insights into ginger-extract-mediated protection against acrylamide-induced liver injury. World J Hepatol 2026; 18(6): 114088
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i6/114088.htm |
| DOI |
https://doi.org/10.4254/wjh.114088 |
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