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1/15/2026 8:12:52 AM | Browse: 1 | Download: 1
Publication Name World Journal of Cardiology
Manuscript ID 114123
Country Nepal
Received
2025-09-15 08:20
Peer-Review Started
2025-09-15 08:20
First Decision by Editorial Office Director
2025-09-20 01:57
Return for Revision
2025-09-20 01:57
Revised
2025-09-22 19:48
Publication Fee Transferred
Second Decision by Editor
2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 10:22
Articles in Press
2025-12-01 10:22
Edit the Manuscript by Language Editor
2025-12-06 22:29
Typeset the Manuscript
2026-01-06 05:47
Publish the Manuscript Online
2026-01-15 08:12
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Meta-Analysis
Article Title Comparison of 6% hydroxyethyl starch 130/0.4 vs 5% albumin in cardiopulmonary bypass for cardiac surgery
Manuscript Source Unsolicited Manuscript
All Author List Ahmed Alqarni, Abdulwahab Algarni and Rejina Chhetri
ORCID
Author(s) ORCID Number
Ahmed Alqarni http://orcid.org/0000-0002-6628-9797
Rejina Chhetri http://orcid.org/0009-0002-2253-783X
Funding Agency and Grant Number
Corresponding Author Rejina Chhetri, Department of Cardiology, Nepalgunj Medical College, Das Bigha, Kohalpur - 11, Kohal 21900, Nepal. rejinachhetri01@gmail.com
Key Words Cardiopulmonary bypass; Cardiac surgery; Hydroxyethyl starch; Albumin; Acute kidney injury; Platelet count; Blood loss
Core Tip This meta-analysis systematically compares 6% hydroxyethyl starch 130/0.4 and 5% human albumin as priming and volume replacement fluids in cardiac surgery with cardiopulmonary bypass. It highlights comparable safety and efficacy profiles between the two colloids in terms of bleeding, transfusion needs, intensive care unit stay, and mortality, while identifying a higher risk of acute kidney injury associated with hydroxyethyl starch. These findings challenge traditional preferences and emphasize the need for individualized fluid choice guided by patient factors and evolving regulatory considerations in perioperative cardiac care.
Publish Date 2026-01-15 08:12
Citation

Alqarni A, Algarni A, Chhetri R. Comparison of 6% hydroxyethyl starch 130/0.4 vs 5% albumin in cardiopulmonary bypass for cardiac surgery. World J Cardiol 2026; 18(1): 114123

URL https://www.wjgnet.com/1949-8462/full/v18/i1/114123.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i1.114123
Full Article (PDF) WJC-18-114123-with-cover.pdf
PRISMA 2009 Checklist 114123-PRISMA-2009-Checklist.pdf
Manuscript File 114123_Auto_Edited_030318.docx
Answering Reviewers 114123-answering-reviewers.pdf
Audio Core Tip 114123-audio.mp3
Biostatistics Review Certificate 114123-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114123-conflict-of-interest-statement.pdf
Copyright License Agreement 114123-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114123-non-native-speakers.pdf
Supplementary Material 114123-supplementary-material.pdf
Peer-review Report 114123-peer-reviews.pdf
Scientific Misconduct Check 114123-scientific-misconduct-check.png
Scientific Editor Work List 114123-scientific-editor-work-list.pdf
CrossCheck Report 114123-crosscheck-report.pdf