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2/6/2026 8:43:36 AM | Browse: 2 | Download: 12
Publication Name World Journal of Diabetes
Manuscript ID 114124
Country India
Received
2025-09-12 10:00
Peer-Review Started
2025-09-15 09:29
First Decision by Editorial Office Director
2025-10-11 03:04
Return for Revision
2025-10-11 03:04
Revised
2025-11-05 01:53
Publication Fee Transferred
Second Decision by Editor
2025-12-12 06:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-19 06:26
Articles in Press
2025-12-19 06:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-27 02:16
Publish the Manuscript Online
2026-02-06 08:43
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biology
Manuscript Type Minireviews
Article Title Gut microbiota dysbiosis, circulating microbial genetic traces, and their role in gestational diabetes
Manuscript Source Invited Manuscript
All Author List Dinakaran Vasudevan
ORCID
Author(s) ORCID Number
Dinakaran Vasudevan http://orcid.org/0000-0003-0593-370X
Funding Agency and Grant Number
Corresponding Author Dinakaran Vasudevan, Senior Scientist, Gut Microbiome Division, Scientific Knowledge on Aging and Neurological Ailments (SKAN) Research Trust, Happiest Health Office, No.141/2, Gate 4, St. John’s Research Institute, 100 Feet Road, KHB Block, John Nagar, Koramangala, Bengaluru 560034, Karnataka, India. dinakaran.svgev@gmail.com
Key Words Gut dysbiosis; Gestational diabetes mellitus; Microbial DNA; Systemic inflammation; Maternal-foetal health; Biomarkers
Core Tip Pregnancy represents a unique metabolic state, where immune tolerance and insulin sensitivity are tightly regulated. Recent evidence suggests that gut microbiota dysbiosis may compromise the intestinal barrier, leading to the release of microbial genetic traces into the bloodstream. These microbial signals can activate host immune pathways and may aggravate systemic inflammation, thereby exacerbating gestational diabetes mellitus. This review highlights emerging insights into the link between gut dysbiosis, microbial translocation into circulation, and the worsening of diabetic outcomes in pregnancy. Understanding this gut-blood axis could open new opportunities for predictive biomarkers and targeted interventions to improve maternal and foetal health.
Publish Date 2026-02-06 08:43
Citation

Vasudevan D. Gut microbiota dysbiosis, circulating microbial genetic traces, and their role in gestational diabetes. World J Diabetes 2026; 17(2): 114124

URL https://www.wjgnet.com/1948-9358/full/v17/i2/114124.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i2.114124
Full Article (PDF) WJD-17-114124-with-cover.pdf
Manuscript File 114124_Auto_Edited_113419.docx
Answering Reviewers 114124-answering-reviewers.pdf
Audio Core Tip 114124-audio.mpeg
Conflict-of-Interest Disclosure Form 114124-conflict-of-interest-statement.pdf
Copyright License Agreement 114124-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114124-non-native-speakers.pdf
Peer-review Report 114124-peer-reviews.pdf
Journal Editor-in-Chief Review Report 114124-journal-editor-in-chief.pdf
Scientific Misconduct Check 114124-scientific-misconduct-check.png
Scientific Editor Work List 114124-scientific-editor-work-list.pdf
CrossCheck Report 114124-crosscheck-report.pdf