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3/14/2026 4:49:28 AM | Browse: 1 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 114142
Country Türkiye
Received
2025-09-12 10:26
Peer-Review Started
2025-09-12 10:26
First Decision by Editorial Office Director
2025-09-28 10:40
Return for Revision
2025-09-28 10:40
Revised
2025-10-27 19:41
Publication Fee Transferred
Second Decision by Editor
2026-01-08 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-08 07:45
Articles in Press
2026-01-08 07:45
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-11 02:10
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Basic Study
Article Title Protective effects of cerium oxide on ibuprofen-induced renal injury in rats with ureteral obstruction
Manuscript Source Invited Manuscript
All Author List Salih Toruk, Avni Babacan, Mustafa Arslan, Volkan Şıvgın, Şaban Cem Sezen and Hakan Boyunağa
ORCID
Author(s) ORCID Number
Salih Toruk http://orcid.org/0000-0003-1975-5350
Mustafa Arslan http://orcid.org/0000-0003-4882-5063
Funding Agency and Grant Number
Corresponding Author Salih Toruk, MD, Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, No. 47 Emniyet Mh. Mevlana Blv., Ankara 06560, Türkiye. salihtoruk@gmail.com
Key Words Cerium oxide; Ibuprofen; Non-steroidal anti-inflammatory drugs; Ureteral obstruction; Oxidative stress; Renal injury
Core Tip This experimental study explores the protective effects of cerium oxide (CeO2), a powerful antioxidant nanoparticle, against renal injury induced by ibuprofen in rats with unilateral ureteral obstruction. Histopathological and biochemical analyses demonstrated that CeO2 significantly reduced tubular degeneration, glomerular vacuolization, and oxidative stress markers in both the obstructed and contralateral kidneys. These results indicate that CeO2 may function as a nephroprotective adjunct during non-steroidal anti-inflammatory drug therapy, potentially mitigating renal damage associated with obstructive uropathy.
Publish Date 2026-03-14 04:49
Citation

Toruk S, Babacan A, Arslan M, Şıvgın V, Sezen ŞC, Boyunağa H. Protective effects of cerium oxide on ibuprofen-induced renal injury in rats with ureteral obstruction. World J Nephrol 2026; 15(1): 114142

URL https://www.wjgnet.com/2220-6124/full/v15/i1/114142.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.114142
Full Article (PDF) WJN-15-114142-with-cover.pdf
The ARRIVE Guidelines 114142-The-ARRIVE-Guidelines.pdf
Manuscript File 114142_Auto_Edited_075730.docx
Answering Reviewers 114142-answering-reviewers.pdf
Audio Core Tip 114142-audio.mp3
Biostatistics Review Certificate 114142-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114142-conflict-of-interest-statement.pdf
Copyright License Agreement 114142-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 114142-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 114142-non-native-speakers.pdf
Peer-review Report 114142-peer-reviews.pdf
Scientific Misconduct Check 114142-scientific-misconduct-check.png
Scientific Editor Work List 114142-scientific-editor-work-list.pdf
CrossCheck Report 114142-crosscheck-report.pdf