Publication Name	World Journal of Meta-Analysis
Manuscript ID	11415
Country	Portugal

Received	2014-05-20 08:20
Peer-Review Started	2014-05-20 21:09
To Make the First Decision	2014-06-27 12:01
Return for Revision	2014-07-04 13:36
Revised	2014-08-17 23:44
Second Decision	2014-11-14 09:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-11-19 10:57
Articles in Press	2014-11-19 10:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-30 10:07
Publish the Manuscript Online	2015-01-20 08:40

ISSN	2308-3840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Meta-Analysis
Article Title	Antithrombotic treatment in chronic heart failure and sinus rhythm: Systematic review
Manuscript Source	Invited Manuscript
All Author List	Daniel Caldeira, Inês Cruz, Rita Calé, Cristina Martins, Helder Pereira, Joaquim J Ferreira, Fausto J Pinto and João Costa
Funding Agency and Grant Number
Corresponding Author	Dr. Daniel Caldeira, Laboratory of Clinical Pharmacology, Faculty of Medicine, University of Lisbon, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal. dgcaldeira@hotmail.com
Key Words	Heart failure; Sinus rhythm; Platelet aggre­gation inhibitors; Anticoagulants
Core Tip	In patients with atrial fibrillation, chronic heart failure (CHF) increases thromboembolic risk and oral anticoagulation is essential to decrease the risk of thromboembolic complications. Evidence suggests a positive association between CHF, impaired hemostasis and thromboembolic events. Whether antithrombotic drugs should be recommended for these patients (in sinus rhythm) is still debated. We looked for the best available evidence and we found 2 studies fulfilling the inclusion criteria. We performed a meta-analysis of antithrombotic drugs vs placebo and strengthened that antithrombotic drugs do not decrease the risk of stroke (fatal or non-fatal) and increase the risk of major bleeding.
Publish Date	2015-01-20 08:40
Citation	Caldeira D, Cruz I, Calé R, Martins C, Pereira H, Ferreira JJ, Pinto FJ, Costa J. Antithrombotic treatment in chronic heart failure and sinus rhythm: Systematic review. World J Meta-Anal 2015; 3(1): 36-42
URL	http://www.wjgnet.com/2308-3840/full/v3/i1/36.htm
DOI	http://dx.doi.org/10.13105/wjma.v3.i1.36

Full Article (PDF)	WJMA-3-36.pdf
Full Article (Word)	WJMA-3-36.doc
Manuscript File	11415-Review.doc
Answering Reviewers	11415-Answering reviewers.pdf
Copyright License Agreement	11415-Copyright assignment.pdf
Peer-review Report	11415-Peer review(s).pdf
Scientific Misconduct Check	11415-CrossCheck.jpg
Scientific Editor Work List	11415-Scientific editor work list.pdf