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Articles Published Processes
2/3/2026 6:28:09 AM | Browse: 1 | Download: 1
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Received |
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2025-09-15 13:20 |
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Peer-Review Started |
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2025-09-15 13:22 |
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First Decision by Editorial Office Director |
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2025-11-18 05:29 |
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Return for Revision |
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2025-11-18 05:29 |
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Revised |
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2025-11-23 09:40 |
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Publication Fee Transferred |
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2025-11-26 06:57 |
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Second Decision by Editor |
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2025-12-16 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-16 03:28 |
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Articles in Press |
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2025-12-16 03:28 |
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Edit the Manuscript by Language Editor |
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2025-12-21 01:08 |
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Typeset the Manuscript |
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2026-01-27 00:35 |
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Publish the Manuscript Online |
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2026-02-03 06:28 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a-/- mice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ke Liu, Xi Zhang, Fa-Zhan Li, Peng-Yuan Zheng and Yang Mi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tianjian Advanced Biomedical Laboratory Key Research and Development Project |
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| Henan Province Natural Science Foundation |
242300421283 |
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| Corresponding Author |
Yang Mi, PhD, Henan Key Laboratory for Helicobacter pylori and Digestive Tract Microecology, The Fifth Affiliated Hospital of Zhengzhou University, No.3 Kangfu Qianjie, Erqi District, Zhengzhou 450052, Henan Province, China. yangmi198@zzu.edu.cn |
| Key Words |
Atp4a gastric intestinal metaplasia models; Biomarkers; Gastric intestinal metaplasia; Organoid; Taurine |
| Core Tip |
Limited treatments for gastric intestinal metaplasia (GIM) are available. This study used Atp4a-/- mice (spontaneous GIM models) and patient-derived GIM organoids to show that taurine ameliorates GIM: It reduces murine gastric mucosal lesions, upregulates the gastric marker MUC5AC, and downregulates intestinal markers (CDX2, MUC2, and TFF3) in both models, suggesting a novel GIM therapeutic strategy. |
| Publish Date |
2026-02-03 06:28 |
| Citation |
Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i2/114161.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i2.114161 |
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