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3/14/2026 4:49:26 AM | Browse: 2 | Download: 15
Publication Name World Journal of Nephrology
Manuscript ID 114165
Country India
Received
2025-09-15 07:29
Peer-Review Started
2025-09-15 07:29
First Decision by Editorial Office Director
2025-09-23 09:36
Return for Revision
2025-09-23 09:36
Revised
2025-10-02 22:31
Publication Fee Transferred
Second Decision by Editor
2025-12-16 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 11:47
Articles in Press
2025-12-16 11:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 03:33
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Prospective Study
Article Title Dual-score framework: National Early Warning Score 2 and quick Sequential Organ Failure Assessment scores in acute pyelonephritis
Manuscript Source Invited Manuscript
All Author List Punith R Jain, Suryaram Aravind, Prajeeth Reddy K, Manikantan Shekar, Velmurugan Palaniyandi, Hariharasudhan Sekar and Sriram Krishnamoorthy
ORCID
Author(s) ORCID Number
Punith R Jain http://orcid.org/0000-0003-0289-3327
Suryaram Aravind http://orcid.org/0000-0003-2568-7219
Prajeeth Reddy K http://orcid.org/0009-0006-4403-2620
Manikantan Shekar http://orcid.org/0000-0003-4616-2884
Velmurugan Palaniyandi http://orcid.org/0009-0008-8127-3946
Hariharasudhan Sekar http://orcid.org/0000-0002-1022-4863
Sriram Krishnamoorthy http://orcid.org/0000-0002-0045-9415
Funding Agency and Grant Number
Corresponding Author Sriram Krishnamoorthy, Head, Professor, Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, No. 1 Ramachandra Nagar, Porur, Chennai 600116, Tamil Nadu, India. sriram.k@sriramachandra.edu.in
Key Words Acute pyelonephritis; Triage; Intervention; In-hospital mortality; quick Sequential Organ Failure Assessment; National Early Warning Score 2; Early warning scores
Core Tip Acute pyelonephritis (APN) is common in urology, but existing studies on early warning scores often mix heterogeneous sepsis cohorts or emphasize stone-related or emphysematous pyelonephritis. Our prospective study is the first to focus exclusively on non-obstructive, non-emphysematous APN, a group frequently overlooked yet clinically challenging. We demonstrate that the National Early Warning Score 2 score reliably identifies patients who require intensive care unit care or urgent intervention, while the quick Sequential Organ Failure Assessment score more accurately predicts mortality. Used together, they provide a complementary dual-score framework for bedside triage and prognostication. This simple approach offers urologists and nephrologists a practical, objective tool to enhance decision-making and improve patient outcomes.
Publish Date 2026-03-14 04:49
Citation

Jain PR, Aravind S, K PR, Shekar M, Palaniyandi V, Sekar H, Krishnamoorthy S. Dual-score framework: National Early Warning Score 2 and quick Sequential Organ Failure Assessment scores in acute pyelonephritis. World J Nephrol 2026; 15(1): 114165

URL https://www.wjgnet.com/2220-6124/full/v15/i1/114165.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.114165
Full Article (PDF) WJN-15-114165-with-cover.pdf
CONSORT 2010 Statement 114165-CONSORT-2010-statement.pdf
Manuscript File 114165_Auto_Edited_060446.docx
Answering Reviewers 114165-answering-reviewers.pdf
Audio Core Tip 114165-audio.m4a
Biostatistics Review Certificate 114165-biostatistics-statement.pdf
Clinical Trial Registration Statement 114165-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 114165-conflict-of-interest-statement.pdf
Copyright License Agreement 114165-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114165-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114165-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114165-non-native-speakers.pdf
Peer-review Report 114165-peer-reviews.pdf
Scientific Misconduct Check 114165-scientific-misconduct-check.png
Scientific Editor Work List 114165-scientific-editor-work-list.pdf
CrossCheck Report 114165-crosscheck-report.pdf