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12/25/2025 3:52:09 AM | Browse: 9 | Download: 32
Publication Name World Journal of Stem Cells
Manuscript ID 114170
Country Pakistan
Received
2025-09-15 03:08
Peer-Review Started
2025-09-15 03:08
First Decision by Editorial Office Director
2025-09-30 08:02
Return for Revision
2025-09-30 08:02
Revised
2025-10-10 16:51
Publication Fee Transferred
Second Decision by Editor
2025-11-11 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-12 03:15
Articles in Press
2025-11-12 03:15
Edit the Manuscript by Language Editor
2025-11-17 18:12
Typeset the Manuscript
2025-12-18 03:06
Publish the Manuscript Online
2025-12-25 03:52
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Adipose tissue as a living drug: Stromal vascular fraction and adipose tissue derived stem cells in regenerative medicine
Manuscript Source Invited Manuscript
All Author List Mahmood S Choudhery, Ahmad Niaz, Taqdees Arif and Ruhma Mahmood
ORCID
Author(s) ORCID Number
Mahmood S Choudhery http://orcid.org/0000-0003-2038-4817
Ahmad Niaz http://orcid.org/0009-0006-9827-9776
Taqdees Arif http://orcid.org/0000-0002-0258-1510
Ruhma Mahmood http://orcid.org/0000-0001-8548-7927
Funding Agency and Grant Number
Corresponding Author Mahmood S Choudhery, Associate Professor, Department of Human Genetics and Molecular Biology, University of Health Sciences, Khayaban-e- Jamia Punjab, Lahore 54000, Punjab, Pakistan. ms20031@yahoo.com
Key Words Living drugs; Adipose tissue; Stromal vascular fraction; Regenerative medicine; Biomolecules; Adipose tissue derived stem cells
Core Tip Living drugs are cell-based therapies composed of viable, metabolically active cells that survive, adapt, and interact within the patient’s body, unlike conventional drugs with fixed chemical structures. Adipose tissue-derived products, such as stromal vascular fraction and adipose-derived stem cells, exemplify living drugs due to their ability to directly differentiate, secrete paracrine factors, modulate immunity, and promote angiogenesis and tissue repair. Stromal vascular fraction provides therapeutic synergy through its heterogeneous cell population, while adipose-derived stem cells offer high yield, accessibility, and potent secretory activity. Together, they represent promising regenerative strategies, shifting treatments toward durable, adaptive, and patient-specific repair.
Publish Date 2025-12-25 03:52
Citation

Choudhery MS, Niaz A, Arif T, Mahmood R. Adipose tissue as a living drug: Stromal vascular fraction and adipose tissue derived stem cells in regenerative medicine. World J Stem Cells 2025; 17(12): 114170

URL https://www.wjgnet.com/1948-0210/full/v17/i12/114170.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i12.114170
Full Article (PDF) WJSC-17-114170-with-cover.pdf
Manuscript File 114170_Auto_Edited_071302.docx
Answering Reviewers 114170-answering-reviewers.pdf
Audio Core Tip 114170-audio.ogg
Conflict-of-Interest Disclosure Form 114170-conflict-of-interest-statement.pdf
Copyright License Agreement 114170-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114170-non-native-speakers.pdf
Peer-review Report 114170-peer-reviews.pdf
Scientific Misconduct Check 114170-scientific-misconduct-check.png
Scientific Editor Work List 114170-scientific-editor-work-list.pdf
CrossCheck Report 114170-crosscheck-report.pdf