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Articles Published Processes
5/13/2026 8:18:33 AM | Browse: 4 | Download: 19
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Received |
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2025-09-15 03:43 |
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Peer-Review Started |
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2025-09-15 03:43 |
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First Decision by Editorial Office Director |
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2025-10-18 02:19 |
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Return for Revision |
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2025-10-18 02:19 |
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Revised |
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2025-10-31 21:10 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-27 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-27 08:02 |
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Articles in Press |
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2026-01-27 08:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-24 02:10 |
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Publish the Manuscript Online |
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2026-05-13 08:18 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Minireviews |
| Article Title |
Role of TRPM4 ion channel in pediatric arrhythmic syndromes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Olesya V Melnik, Olga E Kulichik, Anastasiya K Zaytseva, Olga A Kofeynikova, Svetlana G Fetisova, Svetlana I Tarnovskaya, Yuliya V Fomicheva, Elena S Vasichkina, Boris S Zhorov, Olga V Kalinina and Anna A Kostareva |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Russian Science Foundation |
25-15-00552 |
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| Corresponding Author |
Anna A Kostareva, Director, MD, Professor, Institute of Molecular Biology and Genetics, Department of Molecular Medicine and Cellular Biology, Institution of Medical Education,, Almazov National Medical Research Centre, Akkuratova Street, 2, Saint-Petersburg 197341, Russia. anna.kostareva@ki.se |
| Key Words |
Transient receptor potential channels; Children; Pathophysiology; Arrhythmia; Cardiac conduction |
| Core Tip |
TRPM4 ion channel plays a crucial role in cardiovascular system and myocardial physiology. Mutations in TRPM4 are linked to cardiac conduction disorders and arrhythmic syndromes in children. Current knowledge on the role of TRPM4 variants in pediatric arrhythmic syndromes are summarized along with a discussion of molecular mechanisms of this ion channel dysfunction. Clinical illustrations underscoring the role of TRPM4 in arrhythmic syndromes manifested in childhood are presented. |
| Publish Date |
2026-05-13 08:18 |
| Citation |
Melnik OV, Kulichik OE, Zaytseva AK, Kofeynikova OA, Fetisova SG, Tarnovskaya SI, Fomicheva YV, Vasichkina ES, Zhorov BS, Kalinina OV, Kostareva AA. Role of TRPM4 ion channel in pediatric arrhythmic syndromes. World J Clin Pediatr 2026; 15(2): 114189 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i2/114189.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i2.114189 |
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