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Publication Name World Journal of Gastroenterology
Manuscript ID 114222
Country United States
Received
2025-09-16 04:53
Peer-Review Started
2025-09-16 04:53
First Decision by Editorial Office Director
2025-10-30 09:24
Return for Revision
2025-10-30 09:24
Revised
2025-11-13 12:24
Publication Fee Transferred
2025-11-18 02:40
Second Decision by Editor
2025-12-02 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 03:22
Articles in Press
2025-12-03 03:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 00:52
Publish the Manuscript Online
2026-01-12 09:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Pamela B Sylvestre
ORCID
Author(s) ORCID Number
Pamela B Sylvestre http://orcid.org/0009-0004-3278-7546
Funding Agency and Grant Number
Corresponding Author Pamela B Sylvestre, MD, Professor, Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 240 Albert Sabin Way, MLC1035, Cincinnati, OH 45229, United States. sylvespa@ucmail.uc.edu
Key Words Ulcerative colitis; Colitis; Inflammatory bowel disease; Hydrogen peroxide; Sodium thiosulfate; R-dihydrolipoic acid; Reducing agent; Redox homeostasis; Reactive oxygen species; Case report
Core Tip Reducing agents, sodium thiosulfate and R-dihydrolipoic acid, are safe and highly effective to induce and maintain remission of ulcerative colitis, respectively, without the need for immunosuppressive drugs, even in patients who are refractory or poorly controlled by conventional and advanced therapies.
Publish Date 2026-01-12 09:50
Citation

Sylvestre PB. Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature. World J Gastroenterol 2026; 32(2): 114222

URL https://www.wjgnet.com/1007-9327/full/v32/i2/114222.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i2.114222
Full Article (PDF) WJG-32-114222-with-cover.pdf
CARE Checklist–2016 114222-CARE-Checklist-2016.pdf
Manuscript File 114222_Auto_Edited_063708.docx
Answering Reviewers 114222-answering-reviewers.pdf
Audio Core Tip 114222-audio.m4a
Conflict-of-Interest Disclosure Form 114222-conflict-of-interest-statement.pdf
Copyright License Agreement 114222-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 114222-informed-consent-statement.pdf
Peer-review Report 114222-peer-reviews.pdf
Scientific Misconduct Check 114222-scientific-misconduct-check.png
Scientific Editor Work List 114222-scientific-editor-work-list.pdf
CrossCheck Report 114222-crosscheck-report.pdf