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3/14/2026 4:49:27 AM | Browse: 2 | Download: 10
Publication Name World Journal of Nephrology
Manuscript ID 114239
Country Australia
Received
2025-09-15 07:12
Peer-Review Started
2025-09-15 07:12
First Decision by Editorial Office Director
2025-09-29 08:49
Return for Revision
2025-09-29 08:49
Revised
2025-10-25 08:27
Publication Fee Transferred
Second Decision by Editor
2026-01-07 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-07 09:59
Articles in Press
2026-01-07 09:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-10 09:32
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists
Manuscript Source Invited Manuscript
All Author List Muhammad M Javaid, Gina Tonkin-Hill and Martin Klein
ORCID
Author(s) ORCID Number
Muhammad M Javaid http://orcid.org/0000-0003-2742-9387
Martin Klein http://orcid.org/0009-0001-7755-0735
Funding Agency and Grant Number
Corresponding Author Muhammad M Javaid, Adjunct Associate Professor, Affiliate Associate Professor, Consultant, FASN, FRACP, FRCP, Department of Medicine, South West Healthcare, 25 Ryot Street, Warrnambool 3280, Victoria, Australia. mmjavaid@doctors.org.uk
Key Words Acute kidney injury; Acute tubulointerstitial nephritis; Immune checkpoint inhibitors; Glomerulonephritis; Nephritis; Nephrotoxicity
Core Tip Immune-mediated acute kidney injury is rare in cancer patients treated with immune checkpoint inhibitors. The presenting features are non-specific, making it difficult to distinguish from other more commonly encountered pre-renal and post-renal causes. However, a precise diagnosis is imperative for instigating appropriate management plan. Attention to the presence of risk factors and other associated features can guide further investigations. Confirmation of diagnosis with a kidney biopsy can minimise the risk of inappropriate exposure to immunosuppression in already seriously unwell patient.
Publish Date 2026-03-14 04:49
Citation

Javaid MM, Tonkin-Hill G, Klein M. Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists. World J Nephrol 2026; 15(1): 114239

URL https://www.wjgnet.com/2220-6124/full/v15/i1/114239.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.114239
Full Article (PDF) WJN-15-114239-with-cover.pdf
Manuscript File 114239_Auto_Edited_075730.docx
Answering Reviewers 114239-answering-reviewers.pdf
Audio Core Tip 114239-audio.m4a
Conflict-of-Interest Disclosure Form 114239-conflict-of-interest-statement.pdf
Copyright License Agreement 114239-copyright-assignment.pdf
Peer-review Report 114239-peer-reviews.pdf
Scientific Misconduct Check 114239-scientific-misconduct-check.png
Scientific Editor Work List 114239-scientific-editor-work-list.pdf
CrossCheck Report 114239-crosscheck-report.pdf