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2/6/2026 8:43:30 AM | Browse: 1 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 114252
Country China
Received
2025-09-15 00:32
Peer-Review Started
2025-09-17 00:26
First Decision by Editorial Office Director
2025-09-23 09:39
Return for Revision
2025-09-23 09:39
Revised
2025-10-11 17:53
Publication Fee Transferred
Second Decision by Editor
2025-12-02 06:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 06:13
Articles in Press
2025-12-16 06:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-27 00:30
Publish the Manuscript Online
2026-02-06 08:43
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Basic Study
Article Title Electroacupuncture protects gastric Cajal cells by reducing macrophage pyroptosis in diabetic gastroparesis
Manuscript Source Unsolicited Manuscript
All Author List Ming-Wei Fan, Jin-Lan Tian, Shu-Hui Zhang, Zi-Jian Zhao, Xin-Ru Liu, Cheng-Xia Liu and Yan Chen
ORCID
Author(s) ORCID Number
Ming-Wei Fan http://orcid.org/0000-0002-9833-0037
Shu-Hui Zhang http://orcid.org/0000-0002-4005-0956
Cheng-Xia Liu http://orcid.org/0000-0002-1664-5001
Yan Chen http://orcid.org/0000-0001-5050-9997
Funding Agency and Grant Number
Corresponding Author Yan Chen, PhD, Department of Gastroenterology, Binzhou Medical University Hospital, No. 661 Yellow River Second Road, Bincheng District, Binzhou 256603, Shandong Province, China. chenyanfeihong0906@163.com
Key Words Diabetic gastroparesis; Interstitial cells of Cajal; Pyroptosis; Macrophages; Electroacupuncture
Core Tip For the first time we show that high-frequency electroacupuncture at Zusanli acupoint outperforms low-frequency stimulation in diabetic gastroparesis by simultaneously blocking the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, halting M2-macrophage pyroptosis, curtailing interleukin-1β/interleukin-18 release and thereby rescuing the interstitial cells of Cajal network, offering an immediately translatable, non-drug strategy to restore gastric motility.
Publish Date 2026-02-06 08:43
Citation

Fan MW, Tian JL, Zhang SH, Zhao ZJ, Liu XR, Liu CX, Chen Y. Electroacupuncture protects gastric Cajal cells by reducing macrophage pyroptosis in diabetic gastroparesis. World J Diabetes 2026; 17(2): 114252

URL https://www.wjgnet.com/1948-9358/full/v17/i2/114252.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i2.114252
Full Article (PDF) WJD-17-114252-with-cover.pdf
The ARRIVE Guidelines 114252-The-ARRIVE-Guidelines.pdf
Manuscript File 114252_Auto_Edited_064046.docx
Answering Reviewers 114252-answering-reviewers.pdf
Audio Core Tip 114252-audio.m4a
Biostatistics Review Certificate 114252-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114252-conflict-of-interest-statement.pdf
Copyright License Agreement 114252-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 114252-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 114252-non-native-speakers.pdf
Peer-review Report 114252-peer-reviews.pdf
Journal Editor-in-Chief Review Report 114252-journal-editor-in-chief.pdf
Scientific Misconduct Check 114252-scientific-misconduct-check.png
Scientific Editor Work List 114252-scientific-editor-work-list.pdf
CrossCheck Report 114252-crosscheck-report.pdf