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Articles Published Processes
2/6/2026 8:43:30 AM | Browse: 1 | Download: 0
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Received |
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2025-09-15 00:32 |
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Peer-Review Started |
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2025-09-17 00:26 |
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First Decision by Editorial Office Director |
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2025-09-23 09:39 |
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Return for Revision |
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2025-09-23 09:39 |
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Revised |
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2025-10-11 17:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-02 06:01 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-16 06:13 |
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Articles in Press |
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2025-12-16 06:13 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-27 00:30 |
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Publish the Manuscript Online |
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2026-02-06 08:43 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Basic Study |
| Article Title |
Electroacupuncture protects gastric Cajal cells by reducing macrophage pyroptosis in diabetic gastroparesis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming-Wei Fan, Jin-Lan Tian, Shu-Hui Zhang, Zi-Jian Zhao, Xin-Ru Liu, Cheng-Xia Liu and Yan Chen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yan Chen, PhD, Department of Gastroenterology, Binzhou Medical University Hospital, No. 661 Yellow River Second Road, Bincheng District, Binzhou 256603, Shandong Province, China. chenyanfeihong0906@163.com |
| Key Words |
Diabetic gastroparesis; Interstitial cells of Cajal; Pyroptosis; Macrophages; Electroacupuncture |
| Core Tip |
For the first time we show that high-frequency electroacupuncture at Zusanli acupoint outperforms low-frequency stimulation in diabetic gastroparesis by simultaneously blocking the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, halting M2-macrophage pyroptosis, curtailing interleukin-1β/interleukin-18 release and thereby rescuing the interstitial cells of Cajal network, offering an immediately translatable, non-drug strategy to restore gastric motility. |
| Publish Date |
2026-02-06 08:43 |
| Citation |
Fan MW, Tian JL, Zhang SH, Zhao ZJ, Liu XR, Liu CX, Chen Y. Electroacupuncture protects gastric Cajal cells by reducing macrophage pyroptosis in diabetic gastroparesis. World J Diabetes 2026; 17(2): 114252 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i2/114252.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i2.114252 |
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