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Articles Published Processes
2/26/2026 10:19:37 AM | Browse: 3 | Download: 1
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Received |
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2025-10-28 09:00 |
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Peer-Review Started |
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2025-10-28 09:00 |
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First Decision by Editorial Office Director |
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2025-11-18 02:25 |
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Return for Revision |
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2025-11-18 02:25 |
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Revised |
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2025-12-03 14:26 |
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Publication Fee Transferred |
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2025-12-09 07:33 |
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Second Decision by Editor |
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2026-01-06 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-06 04:49 |
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Articles in Press |
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2026-01-06 04:49 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-05 07:10 |
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Publish the Manuscript Online |
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2026-02-26 10:19 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fu-Lin Lin, Li-Min Zhou, Yun-Jie Ye, Xiao-Long Luo, Xue-Lin Ji, Si-Qi Chen, Ji-Guang Xie, Bing-Feng Jin and Zhen-Dong Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Traditional Chinese Medicine Science and Technology Development Plan in Zhejiang Province of China |
2022ZB131 |
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| Corresponding Author |
Zhen-Dong Liu, MD, Department of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. liudong761@163.com |
| Key Words |
Colorectal cancer; Chemotherapy; Drug assay; Precision medicine |
| Core Tip |
Colorectal cancer (CRC) is one of the most common malignant tumors. Currently, FOLFOX serves as the standard postoperative adjuvant chemotherapy for resectable CRC, while FOLFIRI and FOLFOXIRI are widely used for metastatic or recurrent disease, typically in combination with targeted therapies. The microtumor patient-derived tumor-like cell clusters (PTC) drug sensitivity testing technology involves establishing an in vitro tumor model highly similar to the patient's actual tumor using their own tumor cells. This model is then utilized for drug sensitivity testing, enabling the screening and recommendation of effective treatment regimens while filtering out ineffective options based on therapeutic efficacy. This study primarily evaluates the feasibility of using PTC to guide individualized chemotherapy for CRC patients. |
| Publish Date |
2026-02-26 10:19 |
| Citation |
Lin FL, Zhou LM, Ye YJ, Luo XL, Ji XL, Chen SQ, Xie JG, Jin BF, Liu ZD. Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters. World J Gastrointest Surg 2026; 18(2): 114286 |
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i2/114286.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v18.i2.114286 |
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