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Articles Published Processes
2/6/2026 6:30:42 AM | Browse: 0 | Download: 0
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Received |
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2025-09-16 06:43 |
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Peer-Review Started |
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2025-09-16 06:44 |
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First Decision by Editorial Office Director |
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2025-09-28 06:51 |
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Return for Revision |
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2025-09-28 06:51 |
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Revised |
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2025-10-11 10:42 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-06 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-06 10:06 |
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Articles in Press |
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2026-01-06 10:06 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-02 03:40 |
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Publish the Manuscript Online |
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2026-02-06 06:30 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Microenvironment plays a critical role in modulating tumor cell dormancy: Current perspectives and potential treatment options
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ye-Rong Qian, Peng Liu, Hui Xu, Yi Lv, Xu-Feng Zhang and Jun-Xi Xiang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shaanxi Innovation Capability Support Plan |
No. 2023KJXX-030 |
| Shaanxi Health and Family Planning Commission Project |
No. 2021E018 |
| Noncommunicable Chronic Diseases-National Science and Technology Major Project of China |
No. 2023ZD0502004 |
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| Corresponding Author |
Jun-Xi Xiang, Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi’an Jiaotong University, No. 277 West Yan-ta Road, Xi’an 710061, Shaanxi Province, China. xjx722@163.com |
| Key Words |
Tumor dormancy; Tumor microenvironment; Extracellular matrix; Cancer recurrence; Metastasis |
| Core Tip |
This article explores the critical role of the tumor microenvironment (TME) in regulating tumor dormancy, a state in which malignant cells remain viable but non-proliferative, contributing to metastasis and recurrence. We highlight the dynamic interactions within the TME, including immune cell modulation, extracellular matrix components, and metabolic factors, that maintain dormancy. The article discusses promising therapeutic strategies targeting the TME to either awaken dormant cells for treatment or maintain their quiescence, aiming to improve cancer treatment outcomes and prevent recurrence. |
| Publish Date |
2026-02-06 06:30 |
| Citation |
Qian YR, Liu P, Xu H, Lv Y, Zhang XF, Xiang JX. Microenvironment plays a critical role in modulating tumor cell dormancy: Current perspectives and potential treatment options. World J Clin Oncol 2026; 17(2): 114298 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i2/114298.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i2.114298 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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