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9/16/2014 9:55:00 AM | Browse: 1133 | Download: 909
Publication Name World Journal of Gastroenterology
Manuscript ID 1143
Country Türkiye
Received
2012-11-14 22:03
Peer-Review Started
2012-11-15 15:01
To Make the First Decision
2012-12-28 17:22
Return for Revision
2012-12-28 20:56
Revised
2013-01-15 00:18
Second Decision
2013-02-06 09:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-02-06 11:22
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-03-30 17:16
Typeset the Manuscript
2013-05-16 18:32
Publish the Manuscript Online
2013-05-20 14:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Autobiography
Article Title Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats
Manuscript Source Invited Manuscript
All Author List Ibrahim Akyazi, Evren Eraslan, Ahmet Gülçubuk, Elif Ergül Ekiz, Zeynep L Çırakli, Damla Haktanir, Deniz Aktaran Bala, Mete Özkurt, Erdal Matur and Mukaddes Özcan
Funding Agency and Grant Number
Funding Agency Grant Number
Istanbul University Department of Scientific Research Projects 3101
Corresponding Author Ibrahim Akyazi, DVM, PhD, Department of Physiology, Veterinary Faculty, Istanbul University, 34320 Istanbul, Turkey. iakyazi@istanbul.edu.tr
Key Words Aspirin; Acute pancreatitis; Cerulein; Antioxidant; Cytokines
Core Tip Acute pancreatitis (AP) is an inflammatory and potentially life-threatening disease. An estimated 80000 cases of AP occur each year in the United States. There is no specific cure for AP; therefore, research interest has focused on prevention strategies. In the present study, the effects of a long-term pretreatment with different doses of aspirin, the oldest and most widely used non-steroidal anti-inflammatory drug, were investigated on a AP model in rats. Our results indicated that aspirin pretreatment dose-dependently prevents or ameliorates some hematological, serological and histological alterations caused by cerulein-induced AP.
Publish Date 2013-05-20 14:33
Citation Akyazi I, Eraslan E, Gülçubuk A, Ekiz EE, Çırakli ZL, Haktanir D, Bala DA, Özkurt M, Matur E, Özcan M. Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats. World J Gastroenterol 2013; 19(19): 2894-2903
URL http://www.wjgnet.com/1007-9327/full/v19/i19/2894.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i19.2894
Full Article (PDF) WJG-19-2894.pdf
Manuscript File 1143-Review.doc
Answering Reviewers 1143-Answering reviewers.doc
Copyright License Agreement 1143-Copyright assignment.pdf
Peer-review Report 1143-Peer review(s).docx
Scientific Editor Work List 1143-Scientific editor work list.doc