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Articles Published Processes
9/16/2014 9:55:00 AM | Browse: 1271 | Download: 1103
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Received |
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2012-11-14 22:03 |
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Peer-Review Started |
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2012-11-15 15:01 |
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To Make the First Decision |
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2012-12-28 17:22 |
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Return for Revision |
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2012-12-28 20:56 |
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Revised |
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2013-01-15 00:18 |
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Second Decision |
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2013-02-06 09:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-02-06 11:22 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-03-30 17:16 |
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Typeset the Manuscript |
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2013-05-16 18:32 |
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Publish the Manuscript Online |
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2013-05-20 14:33 |
Category |
Physiology |
Manuscript Type |
Autobiography |
Article Title |
Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats
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Manuscript Source |
Invited Manuscript |
All Author List |
Ibrahim Akyazi, Evren Eraslan, Ahmet Gülçubuk, Elif Ergül Ekiz, Zeynep L Çırakli, Damla Haktanir, Deniz Aktaran Bala, Mete Özkurt, Erdal Matur and Mukaddes Özcan |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Istanbul University Department of Scientific Research Projects |
3101 |
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Corresponding Author |
Ibrahim Akyazi, DVM, PhD, Department of Physiology, Veterinary Faculty, Istanbul University, 34320 Istanbul, Turkey. iakyazi@istanbul.edu.tr |
Key Words |
Aspirin; Acute pancreatitis; Cerulein; Antioxidant; Cytokines |
Core Tip |
Acute pancreatitis (AP) is an inflammatory and potentially life-threatening disease. An estimated 80000 cases of AP occur each year in the United States. There is no specific cure for AP; therefore, research interest has focused on prevention strategies. In the present study, the effects of a long-term pretreatment with different doses of aspirin, the oldest and most widely used non-steroidal anti-inflammatory drug, were investigated on a AP model in rats. Our results indicated that aspirin pretreatment dose-dependently prevents or ameliorates some hematological, serological and histological alterations caused by cerulein-induced AP. |
Publish Date |
2013-05-20 14:33 |
Citation |
Akyazi I, Eraslan E, Gülçubuk A, Ekiz EE, Çırakli ZL, Haktanir D, Bala DA, Özkurt M, Matur E, Özcan M. Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats. World J Gastroenterol 2013; 19(19): 2894-2903 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i19/2894.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i19.2894 |
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