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Articles Published Processes
4/3/2026 6:41:50 AM | Browse: 31 | Download: 107
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Received |
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2025-09-28 08:45 |
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Peer-Review Started |
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2025-09-28 08:46 |
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First Decision by Editorial Office Director |
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2025-10-30 09:28 |
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Return for Revision |
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2025-10-30 09:28 |
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Revised |
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2025-11-14 07:32 |
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Publication Fee Transferred |
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2025-11-20 08:19 |
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Second Decision by Editor |
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2026-01-29 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-29 07:21 |
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Articles in Press |
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2026-01-29 07:21 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-27 02:52 |
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Publish the Manuscript Online |
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2026-04-03 06:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
MiR-200a-3p/ZEB1/IRF1-mediated PANoptosis prompts Xiangshaliujunzi decoction to overcome 5-fluorouracil resistance in gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong Gao, Dong-Feng Yin, Xiang-Rong Xing, Li-Jiang Zhou and Rui Yu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Liaoning University of Traditional Chinese Medicine |
YXIL-2024-1700-0524 |
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| Corresponding Author |
Rui Yu, Department of Technology, Liaoning University of Traditional Chinese Medicine, No. 79 Chongshan East Road, Huanggu District, Shenyang 110032, Liaoning Province, China. ruiyu690923@163.com |
| Key Words |
Xiangshaliujunzi decoction; Chemoresistance; Gastric cancer; MiR-200a-3p; ZEB1; miRNA |
| Core Tip |
Xiangshaliujunzi decoction (XSLJZD) overcomes 5-fluorouracil (5-FU) resistance in gastric cancer by inducing PANoptosis via the miR-200a-3p/ZEB1/IRF1 pathway. In vitro, XSLJZD inhibits viability and promotes cell death. In vivo, combination with 5-FU enhances this effect. This provides a novel traditional Chinese medicine strategy for chemoresistance, though limitations include lack of standalone controls and generalizability validation. |
| Publish Date |
2026-04-03 06:41 |
| Citation |
Gao H, Yin DF, Xing XR, Zhou LJ, Yu R. MiR-200a-3p/ZEB1/IRF1-mediated PANoptosis prompts Xiangshaliujunzi decoction to overcome 5-fluorouracil resistance in gastric cancer. World J Gastroenterol 2026; 32(14): 114331 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i14/114331.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i14.114331 |
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