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3/16/2026 8:22:57 AM | Browse: 3 | Download: 19
Publication Name World Journal of Gastroenterology
Manuscript ID 114335
Country China
Received
2025-09-17 08:01
Peer-Review Started
2025-09-17 08:01
First Decision by Editorial Office Director
2025-10-10 09:25
Return for Revision
2025-10-10 09:25
Revised
2025-10-17 08:54
Publication Fee Transferred
2025-10-19 01:04
Second Decision by Editor
2026-01-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-04 08:06
Articles in Press
2026-01-04 08:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-25 09:02
Publish the Manuscript Online
2026-03-16 08:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Lactobacillus acidophilus attenuates polyethylene glycol-induced susceptibility to Citrobacter rodentium infection via microbiota modulation
Manuscript Source Unsolicited Manuscript
All Author List Guan-Jun Kou, Jing Shen, Li-Xiang Li, Xiu-Li Zuo and Yan-Qing Li
ORCID
Author(s) ORCID Number
Yan-Qing Li http://orcid.org/0000-0003-0575-0399
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82470571
Corresponding Author Yan-Qing Li, Department of Gastroenterology, Qilu Hospital of Shandong University, No. 107 Wenhua West Road, Jinan 250012, Shandong Province, China. liyanqing@sdu.edu.cn
Key Words Polyethylene glycol; Citrobacter rodentium; Enteropathogenic Escherichia coli; Enterohemorrhagic Escherichia coli; Gut microbiota; Lactobacillus acidophilus
Core Tip Although polyethylene glycol is a relevant compound for clinical applications, recent studies suggest that it could potentially alter the colonic microbiota composition, thereby opening ways for opportunistic pathogen colonization and invasion. Therefore, we aimed to shed light to these questions by infecting a murine model with Citrobacter rodentium, a surrogate for enteropathogenic Escherichia coli and enterohemorrhagic Escherichia coli. Furthermore, we investigated whether Lactobacillus acidophilus administration could potentially protect the colon microbiota against such possible alteration and pathogen invasion.
Publish Date 2026-03-16 08:22
Citation

Kou GJ, Shen J, Li LX, Zuo XL, Li YQ. Lactobacillus acidophilus attenuates polyethylene glycol-induced susceptibility to Citrobacter rodentium infection via microbiota modulation. World J Gastroenterol 2026; 32(11): 114335

URL https://www.wjgnet.com/1007-9327/full/v32/i11/114335.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i11.114335
Full Article (PDF) WJG-32-114335-with-cover.pdf
The ARRIVE Guidelines 114335-The-ARRIVE-Guidelines.pdf
Manuscript File 114335_Auto_Edited_072322.docx
Answering Reviewers 114335-answering-reviewers.pdf
Audio Core Tip 114335-audio.mp3
Biostatistics Review Certificate 114335-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114335-conflict-of-interest-statement.pdf
Copyright License Agreement 114335-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 114335-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 114335-non-native-speakers.pdf
Supplementary Material 114335-supplementary-material.pdf
Peer-review Report 114335-peer-reviews.pdf
Scientific Misconduct Check 114335-scientific-misconduct-check.png
Scientific Editor Work List 114335-scientific-editor-work-list.pdf
CrossCheck Report 114335-crosscheck-report.pdf