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12/11/2025 8:20:55 AM | Browse: 2 | Download: 1
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 114341
Country China
Received
2025-09-16 11:36
Peer-Review Started
2025-09-16 11:44
First Decision by Editorial Office Director
2025-09-20 01:50
Return for Revision
2025-09-20 01:50
Revised
2025-09-26 14:22
Publication Fee Transferred
Second Decision by Editor
2025-10-27 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-27 06:43
Articles in Press
2025-10-27 06:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-02 02:04
Publish the Manuscript Online
2025-12-11 08:20
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Editorial
Article Title Cost vs clinical utility on application of large language models in clinical practice: A double-edged sword
Manuscript Source Invited Manuscript
All Author List Sunny Chi Lik Au
ORCID
Author(s) ORCID Number
Sunny Chi Lik Au http://orcid.org/0000-0002-5849-3317
Funding Agency and Grant Number
Corresponding Author Sunny Chi Lik Au, Chief Physician, Clinical Assistant Professor (Honorary), Research Fellow, School of Clinical Medicine, The University of Hong Kong, 9/F, MO Office, Lo Ka Chow Memorial Ophthalmic Centre, No. 19 Eastern Hospital Road, Causeway Bay, Hong Kong 999077, China. kilihcua@gmail.com
Key Words Large language models; Artificial intelligence; ChatGPT; Cost; Patient education
Core Tip As large language models increasingly permeate medical workflows, this study offers insight into 3 areas: Performance parity, cost democratization, and clinical readiness. Perhaps one potentially compelling finding was cost efficiency. Yet cost-effectiveness alone does not ensure clinical utility. Notably, the study relied exclusively on text-based prompts, omitting multimodal data such as photographs or scans. This is an important limitation in a domain like endoscopy, which often can be driven visually. Large language model performance can drop precipitously when deprived of image context. Without multimodal integration, artificial intelligence tools may inevitably fail to capture key diagnostic signals.
Publish Date 2025-12-11 08:20
Citation

Au SCL. Cost vs clinical utility on application of large language models in clinical practice: A double-edged sword. World J Gastrointest Oncol 2025; 17(12): 114341

URL https://www.wjgnet.com/1948-5204/full/v17/i12/114341.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i12.114341
Full Article (PDF) WJGO-17-114341-with-cover.pdf
Manuscript File 114341_Auto_Edited_023108.docx
Answering Reviewers 114341-answering-reviewers.pdf
Audio Core Tip 114341-audio.m4a
Conflict-of-Interest Disclosure Form 114341-conflict-of-interest-statement.pdf
Copyright License Agreement 114341-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114341-non-native-speakers.pdf
Peer-review Report 114341-peer-reviews.pdf
Scientific Misconduct Check 114341-scientific-misconduct-check.png
Scientific Editor Work List 114341-scientific-editor-work-list.pdf
CrossCheck Report 114341-crosscheck-report.pdf