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2/12/2026 11:20:19 AM | Browse: 1 | Download: 1
Publication Name World Journal of Hepatology
Manuscript ID 114346
Country China
Received
2025-09-19 09:08
Peer-Review Started
2025-09-19 09:09
First Decision by Editorial Office Director
2025-09-25 09:20
Return for Revision
2025-09-26 06:08
Revised
2025-11-01 10:59
Publication Fee Transferred
2025-11-08 11:04
Second Decision by Editor
2025-12-11 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-11 08:17
Articles in Press
2025-12-11 08:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-01 10:19
Publish the Manuscript Online
2026-02-12 11:20
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Effects of tenofovir amibufenamide and entecavir on estimated glomerular filtration rate in treatment-naïve patients with chronic hepatitis B
Manuscript Source Unsolicited Manuscript
All Author List Shi-Peng Ma, Liang Wang, Yu-Liang Zhang, Xin Wan, Qian Liu, Yu-Lun Tang, Lajpat-Rai Malhi and Shan-Fei Ge
ORCID
Author(s) ORCID Number
Shi-Peng Ma http://orcid.org/0009-0003-6708-6814
Shan-Fei Ge http://orcid.org/0000-0002-5917-5863
Funding Agency and Grant Number
Funding Agency Grant Number
Chinese Foundation for Hepatitis Prevention and Control Muxin Research Fund of Chronic Hepatitis B MX202418
Corresponding Author Shan-Fei Ge, Department of Infectious Diseases, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Zheng Street, Donghu District, Nanchang 330006, Jiangxi Province, China. geshanfei2010@163.com
Key Words Chronic hepatitis B; Tenofovir amibufenamide; Entecavir; Estimated glomerular filtration rate; Drug safety
Core Tip This study provides the comparison of renal safety between tenofovir amibufenamide (TMF) and entecavir (ETV) in treatment-naive chronic hepatitis B patients. After propensity score matching, TMF showed significantly less decline in estimated glomerular filtration rate over 48 weeks than ETV. Baseline estimated glomerular filtration rate and triglyceride levels independently predicted abnormal renal function, highlighting TMF’s potential renal safety advantage over ETV and offering clinicians important insights for individualized antiviral therapy.
Publish Date 2026-02-12 11:20
Citation

Ma SP, Wang L, Zhang YL, Wan X, Liu Q, Tang YL, Malhi LR, Ge SF. Effects of tenofovir amibufenamide and entecavir on estimated glomerular filtration rate in treatment-naïve patients with chronic hepatitis B. World J Hepatol 2026; 18(2): 114346

URL https://www.wjgnet.com/1948-5182/full/v18/i2/114346.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i2.114346
Full Article (PDF) WJH-18-114346-with-cover.pdf
STROBE Statement 114346-STROBE-statement.pdf
Manuscript File 114346_Auto_Edited_061015.docx
Answering Reviewers 114346-answering-reviewers.pdf
Audio Core Tip 114346-audio.mp3
Biostatistics Review Certificate 114346-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114346-conflict-of-interest-statement.pdf
Copyright License Agreement 114346-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114346-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114346-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114346-non-native-speakers.pdf
Peer-review Report 114346-peer-reviews.pdf
Scientific Misconduct Check 114346-scientific-misconduct-check.png
Scientific Editor Work List 114346-scientific-editor-work-list.pdf
CrossCheck Report 114346-crosscheck-report.pdf