BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/25/2025 3:52:08 AM | Browse: 1 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 114349
Country Bangladesh
Received
2025-09-17 06:38
Peer-Review Started
2025-09-17 06:38
First Decision by Editorial Office Director
2025-10-11 03:10
Return for Revision
2025-10-11 03:10
Revised
2025-10-20 09:18
Publication Fee Transferred
Second Decision by Editor
2025-11-20 02:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-21 10:14
Articles in Press
2025-11-21 10:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-18 03:06
Publish the Manuscript Online
2025-12-25 03:52
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell & Tissue Engineering
Manuscript Type Review
Article Title Hurdles to overcome for mesenchymal stem cell translation from bench to bedside
Manuscript Source Invited Manuscript
All Author List Naiyareen Fareeza Mayeen, Umme Salma, Noor Hayaty Abu Kasim, Okba Mahmoud and Nazmul Haque
ORCID
Author(s) ORCID Number
Naiyareen Fareeza Mayeen http://orcid.org/0009-0007-2470-7149
Umme Salma http://orcid.org/0009-0004-3836-4173
Noor Hayaty Abu Kasim http://orcid.org/0000-0002-8889-842X
Okba Mahmoud http://orcid.org/0000-0002-3355-1429
Nazmul Haque http://orcid.org/0000-0002-8191-8993
Funding Agency and Grant Number
Corresponding Author Nazmul Haque, Chief, Head, PhD, Department of Regenerative Medicine, Concord Stem Cell Limited, 3, Sima Blossom, Road 16, Dhanmondi, Dhaka 1209, Bangladesh. haquen1983@gmail.com
Key Words Regenerative medicine; Clinical translation; Stem cell expansion; Scaffolds; Immunomodulation; Good manufacturing practice
Core Tip Regenerative medicine has been practiced in a variety of settings for decades. It is a multidisciplinary branch of medicine that aims at replacing degenerated cells or regenerating new human cells, tissues, or organs that have been lost or damaged due to the effects of aging, illness, or congenital defects. The main objective of regenerative medicines is to restore normal functions of the cells or tissues in patients affected by degenerative disorders. Mesenchymal stem cells (MSCs) have the potential to cure the most critical regions or take over the function of a wounded organ that is considered beyond repair using conventional therapies. In the last two decades, thousands of in vitro, in vivo, and clinical trials have been conducted using MSCs. Though the regenerative potential of MSCs has been extensively studied, there are still a lot of challenges that need to be addressed for their successful translation from bench to bedside.
Publish Date 2025-12-25 03:52
Citation

Mayeen NF, Salma U, Abu Kasim NH, Mahmoud O, Haque N. Hurdles to overcome for mesenchymal stem cell translation from bench to bedside. World J Stem Cells 2025; 17(12): 114349

URL https://www.wjgnet.com/1948-0210/full/v17/i12/114349.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i12.114349
Full Article (PDF) WJSC-17-114349-with-cover.pdf
Manuscript File 114349_Auto_Edited_071302.docx
Answering Reviewers 114349-answering-reviewers.pdf
Audio Core Tip 114349-audio.mp4
Conflict-of-Interest Disclosure Form 114349-conflict-of-interest-statement.pdf
Copyright License Agreement 114349-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114349-non-native-speakers.pdf
Peer-review Report 114349-peer-reviews.pdf
Scientific Misconduct Check 114349-scientific-misconduct-check.png
Scientific Editor Work List 114349-scientific-editor-work-list.pdf
CrossCheck Report 114349-crosscheck-report.pdf