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2/26/2026 10:19:30 AM | Browse: 3 | Download: 1
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 114417
Country China
Received
2025-09-27 17:13
Peer-Review Started
2025-09-27 17:13
First Decision by Editorial Office Director
2025-10-10 03:02
Return for Revision
2025-10-10 03:02
Revised
2025-10-24 05:41
Publication Fee Transferred
Second Decision by Editor
2025-11-27 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-27 06:36
Articles in Press
2025-11-27 06:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-05 06:32
Publish the Manuscript Online
2026-02-26 10:19
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Acupuncture regulating the gut-brain axis for postoperative ileus: Neuroimmune mechanisms and clinical translation prospects
Manuscript Source Invited Manuscript
All Author List De-Hui Li, Jia Yuan, Chang Qiao, Xiao-Tong Tian and Qian Yang
ORCID
Author(s) ORCID Number
De-Hui Li http://orcid.org/0000-0001-7963-9410
Qian Yang http://orcid.org/0000-0002-0250-7556
Funding Agency and Grant Number
Funding Agency Grant Number
2023 Government-Funded Project of the Outstanding Talents Training Program in Clinical Medicine ZF2023165
Key Research and Development Projects of Hebei Province 18277731D
Natural Science Foundation of Hebei Province H2024423105
Hebei Provincial Administration of Traditional Chinese Medicine, Scientific Research Project 2023045, 2024023
Hebei Institute of Traditional Chinese Medicine Pharmaceutical Preparation Industry Technology Special Project YJY2024006
Scientific Research Project of Health Commission of Hebei Province 20220962, 20240282
Corresponding Author Qian Yang, Chief Physician, Professor, Hebei Key Laboratory of Turbidity Toxin Syndrome, Department of Gastroenterology, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), No. 389 Zhongshan East Road, Shijiazhuang 050011, Hebei Province, China. yang0311qian@126.com
Key Words Clinical translation; Neuroimmunity; Postoperative ileus; Gut-brain axis; Acupuncture
Core Tip Based on emerging evidence for electroacupuncture at Zusanli (ST36) in treating postoperative ileus via the vagus nerve-mediated anti-inflammatory pathway, this article systematically details the mechanisms by which acupuncture regulates gastrointestinal motility through neural, immune, endocrine, and microbial pathways. It provides a strong rationale for integrating acupuncture, an effective non-pharmacological therapy, into enhanced recovery after surgery protocols. Future research focusing on multi-omics technologies, large-scale clinical trials, and microbiota-gut-brain interactions will be crucial for advancing the clinical application of acupuncture in gastrointestinal motility disorders.
Publish Date 2026-02-26 10:19
Citation

Li DH, Yuan J, Qiao C, Tian XT, Yang Q. Acupuncture regulating the gut-brain axis for postoperative ileus: Neuroimmune mechanisms and clinical translation prospects. World J Gastrointest Surg 2026; 18(2): 114417

URL https://www.wjgnet.com/1948-9366/full/v18/i2/114417.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i2.114417
Full Article (PDF) WJGS-18-114417-with-cover.pdf
Manuscript File 114417_Auto_Edited_073449.docx
Answering Reviewers 114417-answering-reviewers.pdf
Audio Core Tip 114417-audio.m4a
Conflict-of-Interest Disclosure Form 114417-conflict-of-interest-statement.pdf
Copyright License Agreement 114417-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114417-non-native-speakers.pdf
Supplementary Material 114417-supplementary-material.pdf
Peer-review Report 114417-peer-reviews.pdf
Scientific Misconduct Check 114417-scientific-misconduct-check.png
Scientific Editor Work List 114417-scientific-editor-work-list.pdf
CrossCheck Report 114417-crosscheck-report.pdf