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Articles Published Processes
3/30/2026 8:58:28 AM | Browse: 31 | Download: 90
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Received |
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2025-10-17 08:51 |
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Peer-Review Started |
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2025-10-17 08:51 |
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First Decision by Editorial Office Director |
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2025-11-11 06:38 |
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Return for Revision |
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2025-11-11 06:38 |
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Revised |
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2025-11-23 06:04 |
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Publication Fee Transferred |
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2025-12-01 01:31 |
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Second Decision by Editor |
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2026-01-04 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-04 05:10 |
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Articles in Press |
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2026-01-04 05:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-19 01:01 |
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Publish the Manuscript Online |
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2026-03-30 08:58 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology |
| Manuscript Type |
Observational Study |
| Article Title |
Serum 5-hydroxytryptamine levels as biomarkers for motor dysfunction and depression in Parkinson’s disease patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Sheng Chen, Si-Yuan Yang, Ke-Yi Lu, Ming Li, Tian Liu, Shi-Guang Zhu, Hai-Long Lu and Kun Hu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Provincial Geriatric Health Scientific Research Project |
LKM2024016 |
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| Corresponding Author |
Kun Hu, Department of Geriatrics, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Xuzhou 221000, Jiangsu Province, China. xyhk4122@163.com |
| Key Words |
Parkinson’s disease; Serum serotonin; Biomarkers; Dyskinesia; Depression; Non-motor symptoms; Serotonergic dysfunction |
| Core Tip |
This study investigated the role of serum serotonin [5-hydroxytryptamine (5-HT)] as a biomarker for complications in Parkinson’s disease (PD). We found that reduced serum 5-HT levels were independently associated with both levodopa-induced dyskinesia and depression, two common motor and non-motor complications of PD. Serum 5-HT showed good discriminative ability for identifying at-risk patients and may provide a simple peripheral marker for early risk stratification and personalized management in PD. |
| Publish Date |
2026-03-30 08:58 |
| Citation |
Chen YS, Yang SY, Lu KY, Li M, Liu T, Zhu SG, Lu HL, Hu K. Serum 5-hydroxytryptamine levels as biomarkers for motor dysfunction and depression in Parkinson’s disease patients. World J Psychiatry 2026; 16(4): 114462 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i4/114462.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i4.114462 |
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