BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/22/2026 8:14:06 AM | Browse: 46 | Download: 155
 |
Received |
|
2025-09-22 03:04 |
|
Peer-Review Started |
|
2025-09-22 03:04 |
|
First Decision by Editorial Office Director |
|
2025-11-14 09:14 |
|
Return for Revision |
|
2025-11-14 09:14 |
|
Revised |
|
2025-11-16 05:24 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-12-26 02:38 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-12-26 08:14 |
|
Articles in Press |
|
2025-12-26 08:14 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-01-15 01:16 |
|
Publish the Manuscript Online |
|
2026-01-22 08:14 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Rhapontin activating nuclear factor erythroid 2-related factor 2 to ameliorate Parkinson’s disease-associated gastrointestinal dysfunction
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Xiao Chen, Na-Qi Sun and Sai-Jun Mo |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Sai-Jun Mo, Associate Professor, PhD, Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhongyuan District, Zhengzhou 450001, Henan Province, China. sjmo@zzu.edu.cn |
| Key Words |
Rhapontin; Gastrointestinal dysfunction; Parkinson’s disease; Nuclear factor erythroid 2-related factor 2; Anti-inflammatory |
| Core Tip |
This commentary argues that realizing rhapontin’s potential in ameliorating Parkinson’s disease (PD)-associated gastrointestinal dysfunction requires a systems-level understanding of its interaction with the gut microbiota and signaling networks beyond nuclear factor erythroid 2-related factor 2 (NRF2) (e.g., nuclear factor kappa-B, adenosine monophosphate-activated protein kinase, sirtuin 1). It emphasizes that rhapontin’s colonic NRF2-mediated local anti-inflammatory effects support PD’s “enteric pathology hypothesis” and highlight colonic NRF2 as a priority intervention target. |
| Publish Date |
2026-01-22 08:14 |
| Citation |
Chen YX, Sun NQ, Mo SJ. Rhapontin activating nuclear factor erythroid 2-related factor 2 to ameliorate Parkinson’s disease-associated gastrointestinal dysfunction. World J Gastroenterol 2026; 32(4): 114468
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i4/114468.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i4.114468 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
