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Articles Published Processes
1/22/2026 8:14:06 AM | Browse: 0 | Download: 0
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Received |
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2025-09-22 03:04 |
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Peer-Review Started |
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2025-09-22 03:04 |
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First Decision by Editorial Office Director |
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2025-11-14 09:14 |
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Return for Revision |
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2025-11-14 09:14 |
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Revised |
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2025-11-16 05:24 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-26 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-26 08:14 |
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Articles in Press |
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2025-12-26 08:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-15 01:16 |
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Publish the Manuscript Online |
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2026-01-22 08:14 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Rhapontin activating nuclear factor erythroid 2-related factor 2 to ameliorate Parkinson’s disease-associated gastrointestinal dysfunction
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Xiao Chen, Na-Qi Sun and Sai-Jun Mo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sai-Jun Mo, Associate Professor, PhD, Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhongyuan District, Zhengzhou 450001, Henan Province, China. sjmo@zzu.edu.cn |
| Key Words |
Rhapontin; Gastrointestinal dysfunction; Parkinson’s disease; Nuclear factor erythroid 2-related factor 2; Anti-inflammatory |
| Core Tip |
This commentary argues that realizing rhapontin’s potential in ameliorating Parkinson’s disease (PD)-associated gastrointestinal dysfunction requires a systems-level understanding of its interaction with the gut microbiota and signaling networks beyond nuclear factor erythroid 2-related factor 2 (NRF2) (e.g., nuclear factor kappa-B, adenosine monophosphate-activated protein kinase, sirtuin 1). It emphasizes that rhapontin’s colonic NRF2-mediated local anti-inflammatory effects support PD’s “enteric pathology hypothesis” and highlight colonic NRF2 as a priority intervention target. |
| Publish Date |
2026-01-22 08:14 |
| Citation |
Chen YX, Sun NQ, Mo SJ. Rhapontin activating nuclear factor erythroid 2-related factor 2 to ameliorate Parkinson’s disease-associated gastrointestinal dysfunction. World J Gastroenterol 2026; 32(4): 114468 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i4/114468.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i4.114468 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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