BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/5/2026 3:46:21 AM | Browse: 6 | Download: 27
 |
Received |
|
2025-09-22 03:22 |
|
Peer-Review Started |
|
2025-09-22 03:23 |
|
First Decision by Editorial Office Director |
|
2025-10-28 10:02 |
|
Return for Revision |
|
2025-10-28 10:02 |
|
Revised |
|
2025-11-08 16:03 |
|
Publication Fee Transferred |
|
2025-11-10 14:17 |
|
Second Decision by Editor |
|
2025-11-18 01:39 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-11-18 09:31 |
|
Articles in Press |
|
2025-11-18 09:31 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-12-26 01:39 |
|
Publish the Manuscript Online |
|
2026-01-05 03:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Review |
| Article Title |
Potential influence of gut microbiota on the process of hypertriglyceridemia-aggravated acute pancreatitis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Fan Song, Yi Liu, Qiao-Man Fei, Chun-Lan Xu and Fan-Pu Ji |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Innovation Foundation for Doctor Dissertation of Northwestern Polytechnical University |
No. CX2023021 |
|
| Corresponding Author |
Fan-Pu Ji, Department of Hepatology, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 Xiwu Road, Xi’an 710004, Shaanxi Province, China. jifanpu1979@163.com |
| Key Words |
Gut microbiota; Hypertriglyceridemia; Gut-pancreas axis; Acute pancreatitis; Microbial-host-isozyme |
| Core Tip |
Current academic consensus is that hypertriglyceridemia (HTG) primarily exacerbates acute pancreatitis (AP) through lipotoxicity. This traditional view emphasizes that in HTG, pancreatic lipase in acinar cells hydrolyzes triglycerides, generating excessive free fatty acids, which exacerbates AP severity. However, recent evidence has increasingly demonstrated the critical role of the gut microbiota in this pathological process. This review explores how gut microbiota dysbiosis mediates the aggravation of AP caused by HTG, focusing on mechanisms such as microbial translocation, immune dysregulation, and metabolites. The novel “microbial-host-isozyme” concept is proposed for precise diagnosis and therapy in HTG-AP. |
| Publish Date |
2026-01-05 03:46 |
| Citation |
Song XF, Liu Y, Fei QM, Xu CL, Ji FP. Potential influence of gut microbiota on the process of hypertriglyceridemia-aggravated acute pancreatitis. World J Gastroenterol 2026; 32(1): 114479 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i1/114479.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i1.114479 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
