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Articles Published Processes
2/11/2015 5:56:00 PM | Browse: 1151 | Download: 1526
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Received |
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2014-05-22 09:29 |
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Peer-Review Started |
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2014-05-22 13:25 |
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To Make the First Decision |
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2014-06-10 13:22 |
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Return for Revision |
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2014-06-18 14:00 |
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Revised |
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2014-07-07 18:21 |
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Second Decision |
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2014-07-25 09:17 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-07-25 09:38 |
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Articles in Press |
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2014-07-25 09:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-28 19:36 |
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Publish the Manuscript Online |
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2015-02-11 17:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Beta-7 integrin controls enterocyte migration in the small intestine
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Elke Kaemmerer, Paula Kuhn, Ursula Schneider, Thomas Clahsen, Min Kyung Jeon, Christina Klaus, Julia Andruszkow, Michael Härer, Sabine Ernst, Angela Schippers, Norbert Wagner and Nikolaus Gassler |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Deutsche Forschungsgemeinschaft |
DFG GA 785/5-1 |
| Deutsche Krebshilfe |
GA 109313 |
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| Corresponding Author |
Nikolaus Gassler, Professor, Institute of Pathology, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany. ngassler@ukaachen.de |
| Key Words |
Barrier function; Cell migration; Inflammatory bowel disease; Integrin; Intercellular junctions |
| Core Tip |
Integrins are involved in migration of epithelial and non-epithelial cells. beta-7-chain integrins are exclusively expressed on leukocytes and important for homing of lymphocytes into the intestinal mucosa. In beta-7 integrin-deficient mice, the number of intraepithelial lymphocytes is drastically decreased and accompanied by a significant increase in enterocyte migration along the crypt-villus axis. This phenomenon is probably mediated by the E-cadherin beta-7 integrin pathway. |
| Publish Date |
2015-02-11 17:56 |
| Citation |
Kaemmerer E, Kuhn P, Schneider U, Clahsen T, Jeon MK, Klaus C, Andruszkow J, Härer M, Ernst S, Schippers A, Wagner N, Gassler N. Beta-7 integrin controls enterocyte migration in the small intestine. World J Gastroenterol 2015; 21(6): 1759-1764 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i6/1759.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i6.1759 |
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