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Articles Published Processes
6/25/2026 8:21:23 AM | Browse: 1 | Download: 0
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Received |
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2025-09-22 01:55 |
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Peer-Review Started |
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2025-09-22 01:55 |
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First Decision by Editorial Office Director |
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2025-10-24 11:06 |
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Return for Revision |
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2025-10-24 11:06 |
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Revised |
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2025-11-06 16:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-04 02:47 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-04 10:49 |
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Articles in Press |
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2026-01-04 10:49 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-18 06:44 |
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Publish the Manuscript Online |
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2026-06-25 08:21 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Correspondence |
| Article Title |
Mesenchymal stromal cell-derived extracellular vesicles as a promising therapeutic candidate for attenuating cellular senescence
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wei Zhang, Jing-Long Luo, Li Xiao and Jian-Guang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jian-Guang Zhang, PhD, /, Xiamen Institute for Food and Drug Quality Control, No. 33 Dongdu Haishan Road, Huli District, Xiamen 361012, Fujian Province, China. jianguangcn@163.com |
| Key Words |
Mesenchymal stromal cells; Extracellular vesicles; Exosomes; Cellular senescence; Aging |
| Core Tip |
This study by Yang et al provided evidence that clinically produced mesenchymal stromal cell-derived extracellular vesicles effectively counteract cellular senescence. They reduce senescence markers and restore collagen expression in aged human dermal fibroblasts, while mitigating oxidative stress and aging-related gene expression in a D-gal-induced aging mouse model. These results highlight the potential of mesenchymal stromal cell-derived extracellular vesicles as a ready-to-use biologic strategy against aging and aging-associated tissue damage, paving the way for their further clinical development. |
| Publish Date |
2026-06-25 08:21 |
| Citation |
Zhang W, Luo JL, Xiao L, Zhang JG. Mesenchymal stromal cell-derived extracellular vesicles as a promising therapeutic candidate for attenuating cellular senescence. World J Stem Cells 2026; 18(6): 114501
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i6/114501.htm |
| DOI |
https://doi.org/10.4252/wjsc.114501 |
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