BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/15/2026 6:06:26 AM | Browse: 3 | Download: 25
Publication Name World Journal of Experimental Medicine
Manuscript ID 114526
Country Egypt
Received
2025-09-22 02:01
Peer-Review Started
2025-09-22 02:01
First Decision by Editorial Office Director
2025-10-29 09:20
Return for Revision
2025-10-29 09:20
Revised
2025-11-06 17:24
Publication Fee Transferred
Second Decision by Editor
2025-12-29 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-29 06:56
Articles in Press
2025-12-29 06:56
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-23 08:23
Publish the Manuscript Online
2026-03-15 06:06
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title Leukoplakia of oral cavity and urinary bladder are premalignant to squamous carcinoma
Manuscript Source Invited Manuscript
All Author List Mohamed Wishahi
ORCID
Author(s) ORCID Number
Mohamed Wishahi http://orcid.org/0000-0002-4559-619X
Funding Agency and Grant Number
Corresponding Author Mohamed Wishahi, MD, PhD, Professor, Department of Urology, Theodor Bilharz Research Institute, Embaba, Giza, Cairo 12411, Egypt. moh.weshahy@gmail.com
Key Words Leukoplakia; Squamous cell carcinoma; Programmed cell death-ligand 1; Immune checkpoint inhibitors; Oral cancer; Bladder cancer
Core Tip Oral leukoplakia and urinary bladder leukoplakia are premalignant lesions that progress to squamous cell carcinoma (SCC), both lesions and their corresponding SCC express programmed cell death-ligand 1 (PD-L1) indicating response to PD-L1 inhibitors. A recent approach with consideration of recent finding of expression of PD-L1, genetic analysis, microenvironment landscape, recruited clinical trials, and animal model studies would advocate possible treatment of oral leukoplakia with PD-L1 inhibitors aiming at cure and prevent progression to SCC.
Publish Date 2026-03-15 06:06
Citation

Wishahi M. Leukoplakia of oral cavity and urinary bladder are premalignant to squamous carcinoma. World J Exp Med 2026; 16(1): 114526

URL https://www.wjgnet.com/2220-315x/full/v16/i1/114526.htm
DOI https://dx.doi.org/10.5493/wjem.v16.i1.114526
Full Article (PDF) WJEM-16-114526-with-cover.pdf
Manuscript File 114526_Auto_Edited_112649.docx
Answering Reviewers 114526-answering-reviewers.pdf
Audio Core Tip 114526-audio.mp3
Conflict-of-Interest Disclosure Form 114526-conflict-of-interest-statement.pdf
Copyright License Agreement 114526-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114526-non-native-speakers.pdf
Peer-review Report 114526-peer-reviews.pdf
Scientific Misconduct Check 114526-scientific-misconduct-check.png
Scientific Editor Work List 114526-scientific-editor-work-list.pdf
CrossCheck Report 114526-crosscheck-report.pdf