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Publication Name World Journal of Hepatology
Manuscript ID 114542
Country Saudi Arabia
Received
2025-09-23 07:31
Peer-Review Started
2025-09-23 07:40
First Decision by Editorial Office Director
2025-09-29 07:35
Return for Revision
2025-09-29 07:35
Revised
2025-10-09 12:50
Publication Fee Transferred
2025-10-11 09:16
Second Decision by Editor
2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 07:19
Articles in Press
2025-12-01 07:19
Edit the Manuscript by Language Editor
2025-12-05 22:13
Typeset the Manuscript
2026-01-13 00:34
Publish the Manuscript Online
2026-01-27 10:12
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Enhanced surgical tolerance of schistosomiasis-induced fibrotic liver following treatment with Ziziphus plant extract
Manuscript Source Unsolicited Manuscript
All Author List Thamer H Alghamdi
ORCID
Author(s) ORCID Number
Thamer H Alghamdi http://orcid.org/0000-0002-7201-2655
Funding Agency and Grant Number
Corresponding Author Thamer H Alghamdi, Associate Professor, Consultant, Department of Surgery, Al-Baha University, Prince Mohammad Bin Saud Road, Al Baha 65716, Saudi Arabia. tthaker@bu.edu.sa
Key Words Schistosomiasis; Oxidative stress; Ziziphus spina-christi leaf extract; Liver resection; Tumor necrosis factor-α; Interferon-γ
Core Tip The present research strongly suggests that Ziziphus spina-christi leaf extract is a powerful agent in protecting the liver from damages induced by Schistosoma mansoni. Furthermore, this study’s data revealed that liver damage is severely influenced by Schistosoma mansoni infection. The Ziziphus spina-christi leaf extract treatment resulted in improvements biochemical parameters, pro-inflammatory cytokines levels, DNA integrity, and pathological liver outcomes.
Publish Date 2026-01-27 10:12
Citation

Alghamdi TH. Enhanced surgical tolerance of schistosomiasis-induced fibrotic liver following treatment with Ziziphus plant extract. World J Hepatol 2026; 18(1): 114542

URL https://www.wjgnet.com/1948-5182/full/v18/i1/114542.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i1.114542
Full Article (PDF) WJH-18-114542-with-cover.pdf
The ARRIVE Guidelines 114542-The-ARRIVE-Guidelines.pdf
Manuscript File 114542_Auto_Edited_021318.docx
Answering Reviewers 114542-answering-reviewers.pdf
Audio Core Tip 114542-audio.mp3
Biostatistics Review Certificate 114542-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114542-conflict-of-interest-statement.pdf
Copyright License Agreement 114542-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 114542-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 114542-non-native-speakers.pdf
Peer-review Report 114542-peer-reviews.pdf
Scientific Misconduct Check 114542-scientific-misconduct-check.png
Scientific Editor Work List 114542-scientific-editor-work-list.pdf
CrossCheck Report 114542-crosscheck-report.pdf