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3/27/2026 12:16:58 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 114569
Country China
Received
2025-11-18 09:23
Peer-Review Started
2025-11-18 09:23
First Decision by Editorial Office Director
2025-12-09 06:54
Return for Revision
2025-12-09 06:54
Revised
2025-12-22 13:30
Publication Fee Transferred
Second Decision by Editor
2026-01-12 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-12 09:45
Articles in Press
2026-01-12 09:45
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 03:51
Publish the Manuscript Online
2026-03-27 12:16
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Adjuvant irinotecan-apatinib therapy for recurrent/metastatic gastric cancer after surgery: A real-world evaluation
Manuscript Source Unsolicited Manuscript
All Author List Jun-Feng Shi, Hui Xu, Jin-Feng Gao and Jian-Bin Wu
ORCID
Author(s) ORCID Number
Jian-Bin Wu http://orcid.org/0009-0007-4868-3137
Funding Agency and Grant Number
Corresponding Author Jian-Bin Wu, MD, Department of Human Resources, Jiangsu Hengrui Medicine Co.,Ltd, No. 1288 Haike Road, Shanghai 200122, China. 18205137866@163.com
Key Words Real-world evidence; Irinotecan; Apatinib; Postoperative recurrence; Metastatic gastric cancer
Core Tip This study presents a real-world data analysis of clinical efficacy outcomes associated with irinotecan-apatinib adjuvant therapy among patients with postoperative recurrent/metastatic gastric cancer (RMGC). We included 124 postsurgical RMGC patients treated from April 2021 to April 2024, all of whom received the S-1 (via intravenous infusion) plus oxaliplatin (via oral administration; S-1+oxaliplatin) regimen. The irinotecan-apatinib adjuvant therapy for these patients demonstrated significant clinical advantages in inhibiting inflammation and serum tumor markers while improving quality of life, which could be a better option for these patients.
Publish Date 2026-03-27 12:16
Citation

Shi JF, Xu H, Gao JF, Wu JB. Adjuvant irinotecan-apatinib therapy for recurrent/metastatic gastric cancer after surgery: A real-world evaluation. World J Gastrointest Surg 2026; 18(3): 114569

URL https://www.wjgnet.com/1948-9366/full/v18/i3/114569.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i3.114569
Full Article (PDF) WJGS-18-114569-with-cover.pdf
Manuscript File 114569_Auto_Edited_093534.docx
Answering Reviewers 114569-answering-reviewers.pdf
Audio Core Tip 114569-audio.mp3
Biostatistics Review Certificate 114569-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114569-conflict-of-interest-statement.pdf
Copyright License Agreement 114569-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114569-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114569-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114569-non-native-speakers.pdf
Peer-review Report 114569-peer-reviews.pdf
Scientific Misconduct Check 114569-scientific-misconduct-check.png
Scientific Editor Work List 114569-scientific-editor-work-list.pdf
CrossCheck Report 114569-crosscheck-report.pdf