BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/27/2026 1:22:06 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 114634
Country China
Received
2025-09-24 09:32
Peer-Review Started
2025-09-24 09:32
First Decision by Editorial Office Director
2025-12-02 07:23
Return for Revision
2025-12-02 07:23
Revised
2025-12-15 12:34
Publication Fee Transferred
Second Decision by Editor
2025-12-26 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-26 05:59
Articles in Press
2025-12-26 05:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-21 04:59
Publish the Manuscript Online
2026-05-27 13:22
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Opinion Review
Article Title Systemic immune-inflammation index and serum lactoferrin: A novel tool for individualized prognostic assessment in elderly colon cancer
Manuscript Source Invited Manuscript
All Author List Shu-Qi Ren, Zhuo-Ling Huang, Zu-Xun Qiu and Chuang Cai
ORCID
Author(s) ORCID Number
Shu-Qi Ren http://orcid.org/0009-0004-9589-199X
Chuang Cai http://orcid.org/0000-0002-9660-0160
Funding Agency and Grant Number
Corresponding Author Chuang Cai, Assistant Professor, PhD, Cancer Research Institute of Zhongshan City, Zhongshan City People's Hospital, No. 2 Sunwen East Road, Zhongshan 528445, Guangdong Province, China. caich6@foxmail.com
Key Words Systemic immune-inflammation index; Serum lactoferrin; Colon cancer; Elder; Prognosis
Core Tip This prospective study identifies elevated preoperative systemic immune-inflammation index (SII) combined with low serum lactoferrin (LF) as independent prognostic biomarkers in elderly colon cancer patients. This cost-effective and easily measurable combination reflects both systemic inflammatory burden and immune-nutritional status, enhancing traditional tumor node metastasis (TNM) staging. It holds substantial potential for individualized postoperative risk stratification in routine clinical practice.
Publish Date 2026-05-27 13:22
Citation

Ren SQ, Huang ZL, Qiu ZX, Cai C. Systemic immune-inflammation index and serum lactoferrin: A novel tool for individualized prognostic assessment in elderly colon cancer. World J Gastrointest Surg 2026; 18(5): 114634

URL https://www.wjgnet.com/1948-9366/full/v18/i5/114634.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i5.114634
Full Article (PDF) WJGS-18-114634-with-cover.pdf
Manuscript File 114634_Auto_Edited_011240.docx
Answering Reviewers 114634-answering-reviewers.pdf
Audio Core Tip 114634-audio.mp3
Conflict-of-Interest Disclosure Form 114634-conflict-of-interest-statement.pdf
Copyright License Agreement 114634-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114634-non-native-speakers.pdf
Peer-review Report 114634-peer-reviews.pdf
Scientific Misconduct Check 114634-scientific-misconduct-check.png
Scientific Editor Work List 114634-scientific-editor-work-list.pdf
CrossCheck Report 114634-crosscheck-report.pdf