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5/25/2026 7:47:54 AM | Browse: 0 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 114668
Country Saudi Arabia
Received
2025-09-26 11:49
Peer-Review Started
2025-09-26 11:49
First Decision by Editorial Office Director
2025-11-18 07:37
Return for Revision
2025-11-18 07:37
Revised
2025-11-25 05:15
Publication Fee Transferred
2025-12-02 19:18
Second Decision by Editor
2026-03-05 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 03:51
Articles in Press
2026-03-05 03:51
Edit the Manuscript by Language Editor
2026-03-11 23:07
Typeset the Manuscript
2026-05-13 01:12
Publish the Manuscript Online
2026-05-25 07:47
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Isolation and proteomic profiling of mesenchymal stem cell-derived extracellular vesicles: Unlocking new frontiers in regenerative and translational medicine
Manuscript Source Unsolicited Manuscript
All Author List Mir Sadat-Ali, Haifa A Al-Turki, Aleem A Khan, Saira M Bannu, Shivaranjani Vutharadhi and Mirza M Baig
ORCID
Author(s) ORCID Number
Mir Sadat-Ali http://orcid.org/0000-0001-8590-0830
Haifa A Al-Turki http://orcid.org/0000-0002-7472-7304
Aleem A Khan http://orcid.org/0000-0001-7075-9037
Funding Agency and Grant Number
Corresponding Author Mir Sadat-Ali, Professor, Professor Emeritus, Department of Orthopedic Surgery, Dallah Hospital, Pobox 40071, AlKhobar 31952, Saudi Arabia. drsadat@hotmail.com
Key Words Extracellular vesicles; Extracellular vesicles analysis; Proteomics; Extracellular vesicles characterization; Isolation methods
Core Tip Stem cell therapy is used to repair diseased or damaged tissue, in regenerative medicine using mesenchymal stem cells (MSCs). The technology of culturing MSCs is expensive and not available everywhere. MSCs have extracellular vesicles derived from MSCs and are gaining attention as a potential therapeutic alternative to MSCs themselves. For such a process to take shape, scientists should be able to isolate and identify individual proteins and their functionality which can be used for therapeutic purposes. We have used the methodology of proteomics and was able to isolate and identify 53 proteins out which 15 proteins can be targeted in the field of regenerative medicine.
Publish Date 2026-05-25 07:47
Citation

Sadat-Ali M, Al-Turki HA, Khan AA, Bannu SM, Vutharadhi S, Baig MM. Isolation and proteomic profiling of mesenchymal stem cell-derived extracellular vesicles: Unlocking new frontiers in regenerative and translational medicine. World J Stem Cells 2026; 18(5): 114668

URL https://www.wjgnet.com/1948-0210/full/v18/i5/114668.htm
DOI https://dx.doi.org/10.4252/wjsc.v18.i5.114668
Full Article (PDF) WJSC-18-114668-with-cover.pdf
Manuscript File 114668_Auto_Edited_082437.docx
Answering Reviewers 114668-answering-reviewers.pdf
Audio Core Tip 114668-audio.m4a
Biostatistics Review Certificate 114668-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114668-conflict-of-interest-statement.pdf
Copyright License Agreement 114668-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 114668-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114668-non-native-speakers.pdf
Peer-review Report 114668-peer-reviews.pdf
Scientific Misconduct Check 114668-scientific-misconduct-check.png
Scientific Editor Work List 114668-scientific-editor-work-list.pdf
CrossCheck Report 114668-crosscheck-report.pdf