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Publication Name World Journal of Cardiology
Manuscript ID 114706
Country Greece
Received
2025-09-26 08:24
Peer-Review Started
2025-09-26 08:26
First Decision by Editorial Office Director
2025-10-29 09:21
Return for Revision
2025-10-29 09:21
Revised
2025-11-02 18:48
Publication Fee Transferred
Second Decision by Editor
2025-12-24 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-24 07:35
Articles in Press
2025-12-24 07:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-02 07:58
Publish the Manuscript Online
2026-02-09 07:34
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Letter to the Editor
Article Title Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction
Manuscript Source Invited Manuscript
All Author List Nikias Milaras, Konstantinos Toutouzas and Skevos Sideris
ORCID
Author(s) ORCID Number
Nikias Milaras http://orcid.org/0000-0001-7312-0976
Skevos Sideris http://orcid.org/0000-0003-3165-224X
Funding Agency and Grant Number
Corresponding Author Nikias Milaras, Department of Cardiology, "Hippokration" General Hospital, Athens 11527, Greece. nikiasmilaras@gmail.com
Key Words Percutaneous coronary intervention; Cardiac catheterization; Frailty; Non-ST-elevation myocardial infarction
Core Tip Frailty influences outcomes in elderly patients with non-ST-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI). In a large United States cohort, PCI reduced in-hospital mortality across all frailty levels, yet benefits declined and complications, length of stay, and costs rose with increasing frailty. These findings highlight that frailty should not preclude PCI but must be routinely assessed to guide individualized decision-making, risk prediction, and resource allocation in acute coronary care.
Publish Date 2026-02-09 07:34
Citation

Milaras N, Toutouzas K, Sideris S. Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction. World J Cardiol 2026; 18(2): 114706

URL https://www.wjgnet.com/1949-8462/full/v18/i2/114706.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i2.114706
Full Article (PDF) WJC-18-114706-with-cover.pdf
Manuscript File 114706_Auto_Edited_114715.docx
Answering Reviewers 114706-answering-reviewers.pdf
Audio Core Tip 114706-audio.mp3
Conflict-of-Interest Disclosure Form 114706-conflict-of-interest-statement.pdf
Copyright License Agreement 114706-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114706-non-native-speakers.pdf
Peer-review Report 114706-peer-reviews.pdf
Scientific Misconduct Check 114706-scientific-misconduct-check.png
Scientific Editor Work List 114706-scientific-editor-work-list.pdf
CrossCheck Report 114706-crosscheck-report.pdf