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Articles Published Processes
8/20/2026 6:54:19 AM | Browse: 1 | Download: 0
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Received |
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2025-09-27 17:22 |
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Peer-Review Started |
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2025-09-27 17:23 |
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First Decision by Editorial Office Director |
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2025-11-10 06:33 |
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Return for Revision |
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2025-11-10 06:33 |
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Revised |
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2025-11-26 14:18 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-19 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-19 07:53 |
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Articles in Press |
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2026-01-19 07:53 |
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Edit the Manuscript by Language Editor |
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2026-01-24 19:32 |
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Typeset the Manuscript |
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2026-08-14 01:20 |
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Publish the Manuscript Online |
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2026-08-20 06:54 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Editorial |
| Article Title |
Extracellular vesicle therapeutics for cardiac regeneration: Overcoming standardization hurdles
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rui-Qin Xue, Jun-Yan Hou, Wei-Xi Gao, Lin-Hao Zhang, Yu-Xiang Liu and Xiao-Shuang Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Research Project of Basic Research Program in Shanxi Province |
202203021221268 |
| National Natural Science Foundation of China |
82305030 |
| Special Fund from Medicinal Basic Research Innovation Center of Chronic Kidney Disease, Ministry of Education, Shanxi Medical University |
CKD/SXMU-2024-04 |
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| Corresponding Author |
Yu-Xiang Liu, MD, PhD, Professor, Department of Nephrology, Shanxi Provincial People’s Hospital, The Fifth Clinical Medical College of Shanxi Medical University, No. 29 Shuangta Temple Street, Yingze District, Taiyuan 030012, Shanxi Province, China. liuyuxiang@tmu.edu.cn |
| Key Words |
Mesenchymal stem cells; Extracellular vesicles; Exercise training; Myocardial infarction; Combination therapy; Clinical translation; Cardiac regeneration |
| Core Tip |
This article systematically summarizes the findings and mechanisms elucidated by ShamsEldeen et al and, based on current preclinical evidence, outlines the key challenges and countermeasures in translating extracellular vesicle - based therapies into clinical practice - paving the way for future clinical applications that may benefit a broader patient population, including but not limited to those with cardiac diseases. Furthermore, it provides a preliminary outlook on strategies for optimizing therapeutic efficacy, scaling up production, and expanding into diverse disease areas. |
| Publish Date |
2026-08-20 06:54 |
| Citation |
Xue RQ, Hou JY, Gao WX, Zhang LH, Liu YX, Zhou XS. Extracellular vesicle therapeutics for cardiac regeneration: Overcoming standardization hurdles. World J Stem Cells 2026; 18(8): 114716
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i8/114716.htm |
| DOI |
https://doi.org/10.4252/wjsc.114716 |
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