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Articles Published Processes
2/26/2026 10:19:30 AM | Browse: 3 | Download: 1
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Received |
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2025-09-28 15:14 |
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Peer-Review Started |
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2025-09-28 15:14 |
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First Decision by Editorial Office Director |
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2025-10-17 06:31 |
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Return for Revision |
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2025-10-17 06:31 |
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Revised |
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2025-10-31 10:17 |
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Publication Fee Transferred |
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2025-11-07 01:37 |
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Second Decision by Editor |
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2025-12-05 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-05 07:57 |
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Articles in Press |
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2025-12-05 07:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-05 01:08 |
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Publish the Manuscript Online |
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2026-02-26 10:19 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Neurotrophin-3 rs1805149A>G variant in Hirschsprung disease: An investigative study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Gang Xu, Yan-Qing Liu, Meng-Long Lan, Fei Liu, Hui-Min Xia and Ji-Xiao Zeng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Science and Technology Project of Guangzhou |
202206080002 |
| National Natural Science Foundation of China |
82170528 |
| Guangzhou Science and Technology Plan of Municipal University (Institute) Joint Funding |
SL2024A03J01490 |
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| Corresponding Author |
Ji-Xiao Zeng, Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 318 Renmin Road, Guangzhou 510623, Guangdong Province, China. zengjixiao@163.com |
| Key Words |
Hirschsprung disease; Neurotrophin-3; Single nucleotide polymorphism; Enteric nervous system; Genetic susceptibility |
| Core Tip |
This case-control study explores the association between the neurotrophin-3 (NTF3) rs1805149A>G variant and Hirschsprung disease (HSCR) susceptibility in a southern Chinese Han population. Despite previous reports implicating NTF3 in HSCR pathogenesis, no significant association was found in this cohort. The results highlight the complexity of HSCR's genetic architecture and suggest that other factors, such as rare variants or multi-gene interactions, may play a more substantial role in its development. Further studies with larger sample sizes and diverse populations are needed to clarify the genetic basis of HSCR. |
| Publish Date |
2026-02-26 10:19 |
| Citation |
Xu XG, Liu YQ, Lan ML, Liu F, Xia HM, Zeng JX. Neurotrophin-3 rs1805149A>G variant in Hirschsprung disease: An investigative study. World J Gastrointest Surg 2026; 18(2): 114724 |
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i2/114724.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v18.i2.114724 |
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