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Articles Published Processes
4/21/2026 8:57:45 AM | Browse: 4 | Download: 11
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Received |
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2025-09-29 02:21 |
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Peer-Review Started |
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2025-09-29 05:41 |
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First Decision by Editorial Office Director |
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2025-10-31 09:17 |
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Return for Revision |
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2025-11-03 07:07 |
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Revised |
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2025-11-11 07:13 |
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Publication Fee Transferred |
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2025-11-23 06:05 |
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Second Decision by Editor |
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2026-01-09 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-09 06:10 |
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Articles in Press |
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2026-01-09 06:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-09 01:05 |
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Publish the Manuscript Online |
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2026-04-21 08:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Integrated transcriptomics and metabolomics reveal neutrophil extracellular trap associated with interferon treatment for chronic hepatitis B
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiang-Yang Ye, Xiong-Zhi He, Zhen-Ting Hu, Feng-Feng Zheng, Xiao-Gang Huang, Xue-Mei Xie, Fei-Hua Chen, Han-Bing Ou and Rong-Xian Qiu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Rong-Xian Qiu, Department of Infectious Diseases, The Affiliated Hospital of Putian University, No. 181 Meiyuan East Road, Putian 351100, Fujian Province, China. 18850959988@163.com |
| Key Words |
Interferon; Neutrophil extracellular trap; Chronic hepatitis B; Hepatitis B virus; Transcriptomic and metabolomic |
| Core Tip |
Chronic hepatitis B is a significant global health issue, and interferon (IFN) is one of the main first-line therapies for chronic hepatitis B. Non-targeted transcriptomic and metabolomic analyses revealed that IFN-related immune pathways and neutrophil extracellular trap formation were the most significantly altered pathways after IFN treatment. Core components of neutrophil extracellular traps including histones were notably increased and potentially enhance the antiviral response. |
| Publish Date |
2026-04-21 08:57 |
| Citation |
Ye XY, He XZ, Hu ZT, Zheng FF, Huang XG, Xie XM, Chen FH, Ou HB, Qiu RX. Integrated transcriptomics and metabolomics reveal neutrophil extracellular trap associated with interferon treatment for chronic hepatitis B. World J Hepatol 2026; 18(4): 114804 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i4/114804.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i4.114804 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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